Protein Alignment thetaTry and KLK2

DIOPT Version :10

• Sequence 1: NP_523693.1
• Gene: thetaTry / 36218
• FlyBaseID: FBgn0011555
• Length: 262
• Species: Drosophila melanogaster
• Sequence 2: NP_005542.1
• Gene: KLK2 / 3817
• HGNCID: 6363
• Length: 261
• Species: Homo sapiens
• Alignment Length: 278
• Identity: 92/278 - (33%)
• Similarity: 137/278 - (49%)
• Gaps: 55/278 - (19%)

  Fly     5 VVLLVCLAVGSACAGTVGVSNGDPFEREGRIVGGEDTTIGAHPYQVSLQTKSGSHFCGGSLINED 69
            :||.:.|:||  |.|.|.:.       :.|||||.:....:.|:||::.:...:| |||.|::..
Human     4 LVLSIALSVG--CTGAVPLI-------QSRIVGGWECEKHSQPWQVAVYSHGWAH-CGGVLVHPQ 58

  Fly    70 TVVTAAHCLVGRKVSKVFVRLG---------------------STLYNEGGIVVAVRELAYNEDY 113
            .|:||||||  :|.|:|:  ||                     ..|||..  ::..:.|..:||
Human    59 WVLTAAHCL--KKNSQVW--LGRHNLFEPEDTGQRVPVSHSFPHPLYNMS--LLKHQSLRPDED- 116

  Fly   114 NSKTMEYDVGILKLDEKVKETENIRYIELATETPPTGTTAVVTGWGS---KCYFWCMTLPKTLQE 175
                ..:|:.:|:|.|..|.|:.::.:.|.|:.|..|||...:||||   :.:.    .|::||.
Human   117 ----SSHDLMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFL----RPRSLQC 173

  Fly   176 VYVNIVDWKTCASDEYKYGEIIYDSMVCA--YEKKKDACQGDSGGPLAVGNTLVGIVSWG-YACA 237
            |.::::....||.   .|.|.:.:.|:||  :...||.|.|||||||.....|.||.||| ..||
Human   174 VSLHLLSNDMCAR---AYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCA 235

  Fly   238 SNLLPGVYSDVPALRKWI 255
            ....|.||:.|...||||
Human   236 LPEKPAVYTKVVHYRKWI 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
thetaTry	NP_523693.1	Tryp_SPc	34..255	CDD:214473	82/247 (33%)
KLK2	NP_005542.1	Tryp_SPc	25..256	CDD:238113	83/248 (33%)