Protein Alignment thetaTry and KLK3

DIOPT Version :10

• Sequence 1: NP_523693.1
• Gene: thetaTry / 36218
• FlyBaseID: FBgn0011555
• Length: 262
• Species: Drosophila melanogaster
• Sequence 2: NP_001639.1
• Gene: KLK3 / 354
• HGNCID: 6364
• Length: 261
• Species: Homo sapiens
• Alignment Length: 239
• Identity: 78/239 - (32%)
• Similarity: 119/239 - (49%)
• Gaps: 26/239 - (10%)

  Fly    34 RIVGGEDTTIGAHPYQVSLQTKSGSHFCGGSLINEDTVVTAAHCLVGRKVSKVFVRLG-STLYN- 96
            |||||.:....:.|:|| |....|...|||.|::...|:|||||:..:.|    :.|| .:|::
Human    24 RIVGGWECEKHSQPWQV-LVASRGRAVCGGVLVHPQWVLTAAHCIRNKSV----ILLGRHSLFHP 83

  Fly    97 -EGGIVVAVRELAYNEDYNSKTME-----------YDVGILKLDEKVKETENIRYIELATETPPT 149
             :.|.|..|.....:..|:...::           :|:.:|:|.|..:.|:.::.::|.|:.|..
Human    84 EDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQEPAL 148

  Fly   150 GTTAVVTGWGSKCYFWCMTLPKTLQEVYVNIVDWKTCASDEYKYGEIIYDSMVCA--YEKKKDAC 212
            |||...:||||......:| ||.||.|.::::....||.   .:.:.:...|:||  :...|..|
Human   149 GTTCYASGWGSIEPEEFLT-PKKLQCVDLHVISNDVCAQ---VHPQKVTKFMLCAGRWTGGKSTC 209

  Fly   213 QGDSGGPLAVGNTLVGIVSWG-YACASNLLPGVYSDVPALRKWI 255
            .|||||||.....|.||.||| ..||....|.:|:.|...||||
Human   210 SGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWI 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
thetaTry	NP_523693.1	Tryp_SPc	34..255	CDD:214473	76/237 (32%)
KLK3	NP_001639.1	Tryp_SPc	25..256	CDD:238113	77/238 (32%)