Protein Alignment thetaTry and TMPRSS7

DIOPT Version :10

• Sequence 1: NP_523693.1
• Gene: thetaTry / 36218
• FlyBaseID: FBgn0011555
• Length: 262
• Species: Drosophila melanogaster
• Sequence 2: NP_001382436.1
• Gene: TMPRSS7 / 344805
• HGNCID: 30846
• Length: 843
• Species: Homo sapiens
• Alignment Length: 282
• Identity: 96/282 - (34%)
• Similarity: 133/282 - (47%)
• Gaps: 51/282 - (18%)

  Fly     9 VCLAVGSA-CAGTVGVSNGDPFEREG-----------RIVGGEDTTIGAHPYQVSLQTKSGSHFC 61
            :|....:| |.|||...:|.  :.||           ||:||.||..|..|:||||.. .||.:|
Human   570 ICFRKQNAKCDGTVDCPDGS--DEEGCTCSRSSSALHRIIGGTDTLEGGWPWQVSLHF-VGSAYC 631

  Fly    62 GGSLINEDTVVTAAHCLVGRKVSKV---FVRLGSTLYNEGGIVVAVRELAYNEDYNSKTMEYDVG 123
            |.|:|:.:.:::||||..|.::|..   ...||..:......|..||.:..:|.|||:|.:||:.
Human   632 GASVISREWLLSAAHCFHGNRLSDPTPWTAHLGMYVQGNAKFVSPVRRIVVHEYYNSQTFDYDIA 696

  Fly   124 ILKLDEKVKETENIRYIELATETPPT------GTTAVVTGWG------SKCYFWCMTLPKTLQEV 176
            :|:|  .:...|.::.:......|||      |....|||||      :|...       .||:.
Human   697 LLQL--SIAWPETLKQLIQPICIPPTGQRVRSGEKCWVTGWGRRHEADNKGSL-------VLQQA 752

  Fly   177 YVNIVDWKTCASDEYKYGEIIYDSMVCA--YEKKKDACQGDSGGPLAVGN------TLVGIVSWG 233
            .|.::|...|.|   .|| ||...|:||  ...|:|||:|||||||:...      .|.||||||
Human   753 EVELIDQTLCVS---TYG-IITSRMLCAGIMSGKRDACKGDSGGPLSCRRKSDGKWILTGIVSWG 813

  Fly   234 YACASNLLPGVYSDVPALRKWI 255
            :.......||||:.|.....||
Human   814 HGSGRPNFPGVYTRVSNFVPWI 835

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
thetaTry	NP_523693.1	Tryp_SPc	34..255	CDD:214473	85/243 (35%)
TMPRSS7	NP_001382436.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	27..67
		SEA	108..207	CDD:460188
		CUB	247..359	CDD:238001
		LDLa	484..518	CDD:238060
		LDLa	559..594	CDD:238060	8/25 (32%)
		Tryp_SPc	605..835	CDD:214473	85/243 (35%)