Protein Alignment thetaTry and OVCH2

DIOPT Version :10

• Sequence 1: NP_523693.1
• Gene: thetaTry / 36218
• FlyBaseID: FBgn0011555
• Length: 262
• Species: Drosophila melanogaster
• Sequence 2: XP_047282834.1
• Gene: OVCH2 / 341277
• HGNCID: 29970
• Length: 569
• Species: Homo sapiens
• Alignment Length: 296
• Identity: 83/296 - (28%)
• Similarity: 135/296 - (45%)
• Gaps: 49/296 - (16%)

  Fly     2 HRLVVLL------------VCLAVGSACA-GTVGVSNGDPFEREGRIVGGEDTTIGAHPYQVSLQ 53
            ::|::||            :.|....:|. ..|.|...:.|....||:||.....|::|:||||:
Human    10 NKLILLLGIVFFERGKSATLSLPKAPSCGQSLVKVQPWNYFNIFSRILGGSQVEKGSYPWQVSLK 74

  Fly    54 TKSGSHFCGGSLINEDTVVTAAHCLVGRK-VSKVFVRLGS---TLYNEGGIVVAVRELAYNEDYN 114
            .:. .|.||||:::...|:|||||:..|. ||.:.|..|.   :..:.|...:.:..:..:..::
Human    75 QRQ-KHICGGSIVSPQWVITAAHCIANRNIVSTLNVTAGEYDLSQTDPGEQTLTIETVIIHPHFS 138

  Fly   115 S-KTMEYDVGILKLDEKVKETENIRYIEL--ATETPPTGTTAVVTGWGSKCYFWCMT----LPKT 172
            : |.|:||:.:||:....:....:..|.|  ..|....|......|||.      :|    |.:.
Human   139 TKKPMDYDIALLKMAGAFQFGHFVGPICLPELREQFEAGFICTTAGWGR------LTEGGVLSQV 197

  Fly   173 LQEVYVNIVDWKTCASDEYKYGE-IIYDSMVCA--YEKKKDACQGDSGGPLAVGN-----TLVGI 229
            ||||.:.|:.|:.|.:....... |...:.:|.  .:..:|||||||||.|...|     ||.|:
Human   198 LQEVNLPILTWEECVAALLTLKRPISGKTFLCTGFPDGGRDACQGDSGGSLMCRNKKGAWTLAGV 262

  Fly   230 VSWGYACA----SNL------LPGVYSDVPALRKWI 255
            .|||..|.    :|:      .||:::|:..:..||
Human   263 TSWGLGCGRGWRNNVRKSDQGSPGIFTDISKVLPWI 298

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
thetaTry	NP_523693.1	Tryp_SPc	34..255	CDD:214473	73/249 (29%)
OVCH2	XP_047282834.1	Tryp_SPc	56..301	CDD:238113	74/250 (30%)
		CUB	320..424	CDD:238001
		CUB	435..546	CDD:238001