Protein Alignment thetaTry and PRSS38

DIOPT Version :10

• Sequence 1: NP_523693.1
• Gene: thetaTry / 36218
• FlyBaseID: FBgn0011555
• Length: 262
• Species: Drosophila melanogaster
• Sequence 2: NP_898885.1
• Gene: PRSS38 / 339501
• HGNCID: 29625
• Length: 326
• Species: Homo sapiens
• Alignment Length: 267
• Identity: 83/267 - (31%)
• Similarity: 122/267 - (45%)
• Gaps: 45/267 - (16%)

  Fly    20 TVGVSNGDPFEREGRIVGGEDTTIGAHPYQVSLQTKSGSHFCGGSLINEDTVVTAAHCLVGRKVS 84
            |..|:.|.| ..||:|:||........|:|||:. .:|.|.||||::||..|::||||....|..
Human    46 TGSVACGRP-SMEGKILGGVPAPERKWPWQVSVH-YAGLHVCGGSILNEYWVLSAAHCFHRDKNI 108

  Fly    85 KVF----------VRLGSTLYNEGGIVVAVRELAYNEDYNS-KTMEYDVGILKLDEKVKETENIR 138
            |::          |....|.:.|      |..:..:..|.. ..:..||.:::|..::..:|::.
Human   109 KIYDMYVGLVNLRVAGNHTQWYE------VNRVILHPTYEMYHPIGGDVALVQLKTRIVFSESVL 167

  Fly   139 YIELAT-ETPPTGTTAVVTGWGSKCYFWCMTLPK------TLQEVYVNIVDWKTCASDEYKYGEI 196
            .:.||| |...|......||||        .:.|      .|||:.:.::....|   ...||.:
Human   168 PVCLATPEVNLTSANCWATGWG--------LVSKQGETSDELQEMQLPLILEPWC---HLLYGHM 221

  Fly   197 IY--DSMVCAYE--KKKDACQGDSGGPLAV----GNTLVGIVSWGYACASNLLPGVYSDVPALRK 253
            .|  ..|:||.:  ..|..|:|||||||..    ....:||||||..|::.|.||||:.|....|
Human   222 SYIMPDMLCAGDILNAKTVCEGDSGGPLVCEFNRSWLQIGIVSWGRGCSNPLYPGVYASVSYFSK 286

  Fly   254 WILNASE 260
            ||.:..|
Human   287 WICDNIE 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
thetaTry	NP_523693.1	Tryp_SPc	34..255	CDD:214473	74/246 (30%)
PRSS38	NP_898885.1	Tryp_SPc	60..291	CDD:238113	76/248 (31%)