DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment thetaTry and Prss53

DIOPT Version :9

Sequence 1:	NP_523693.1	Gene:	thetaTry / 36218	FlyBaseID:	FBgn0011555	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_001074737.1	Gene:	Prss53 / 330657	MGIID:	2652890	Length:	552	Species:	Mus musculus

Alignment Length:	282	Identity:	76/282 - (26%)
Similarity:	118/282 - (41%)	Gaps:	59/282 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 VVLLVCLAVGSACAGTVGVSNGDPFEREGRIVGGEDTTIGAHPYQVSLQTKSGSHFCGGSLINED 69
            ||::..|.......|..|  .|.|..:||..:.||      .|:|.|:: :.|.|.|.|||:.:.
Mouse    15 VVVIEGLQAAQRACGQRG--PGPPEPQEGNTLPGE------WPWQASVR-RQGVHICSGSLVADT 70

  Fly    70 TVVTAAHC---LVGRKVSKVFVRLGSTLYNE----GGIVVAVRELAYNEDYNSKTMEYDVGILKL 127
            .|:|||||   :...::|...|.||| |..|    |...|.|..|...:.||..:...|:.:|:|
Mouse    71 WVLTAAHCFEKMATAELSSWSVVLGS-LKQEGQSPGAEEVGVAALQLPKAYNHYSQGSDLALLQL 134

  Fly   128 DEKVKETENIRYIELATETP----PTGTTAVVTGWGSKCYFWCMTLPKTLQEVYVNIVDWKTCAS 188
            .....:|      .|....|    |.|.:...|||...    ...:.:||:.:.:.::...||
Mouse   135 THPTVQT------TLCLPQPTYHFPFGASCWATGWDQN----TSDVSRTLRNLRLRLISRPTC-- 187

  Fly   189 DEYKYGEIIYD-------------SMVC--AYEKKKDACQGDSGGPLAV----GNTL-VGIVSWG 233
                  ..:|:             .|:|  |...::..||||||||:..    |:.: |||:|:.
Mouse   188 ------NCLYNRLHQRLLSNPARPGMLCGGAQPGEQGPCQGDSGGPVMCREPDGHWVQVGIISFT 246

  Fly   234 YACASNLLPGVYSDVPALRKWI 255
            ..||....|.:.:|:.....|:
Mouse   247 SKCAQEDTPVLLTDMAVHSSWL 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
thetaTry	NP_523693.1	Tryp_SPc	34..255	CDD:214473	66/251 (26%)
thetaTry	NP_523693.1	Tryp_SPc	35..255	CDD:238113	66/250 (26%)
Prss53	NP_001074737.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	27..46		6/20 (30%)
		Tryp_SPc	45..271	CDD:238113	67/250 (27%)
		Tryp_SPc	311..522	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839481
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030