Protein Alignment thetaTry and GZMM

DIOPT Version :10

• Sequence 1: NP_523693.1
• Gene: thetaTry / 36218
• FlyBaseID: FBgn0011555
• Length: 262
• Species: Drosophila melanogaster
• Sequence 2: NP_005308.2
• Gene: GZMM / 3004
• HGNCID: 4712
• Length: 257
• Species: Homo sapiens
• Alignment Length: 268
• Identity: 83/268 - (30%)
• Similarity: 132/268 - (49%)
• Gaps: 32/268 - (11%)

  Fly     1 MHRLVVLLVCLAVGSACAGTVGVSNGDPFEREGRIVGGEDTTIGAHPYQVSLQTKSGSHFCGGSL 65
            |...|..|:.||:|   |.:||.|.|.      :|:||.:....:.||..||| ::|||.|||.|
Human     1 MEACVSSLLVLALG---ALSVGSSFGT------QIIGGREVIPHSRPYMASLQ-RNGSHLCGGVL 55

  Fly    66 INEDTVVTAAHCLVGRKVSKVFVRLGSTLYNEGGIVVAVRELAYNEDYNS-KTMEYDVGILKLDE 129
            ::...|:|||||| .::::::.:.||....:..|:...::....:..|.. ..:|.|:.:|:||.
Human    56 VHPKWVLTAAHCL-AQRMAQLRLVLGLHTLDSPGLTFHIKAAIQHPRYKPVPALENDLALLQLDG 119

  Fly   130 KVKETENIRYIELAT--ETPPTGTTAVVTGWGSKCYFWCMT-----LPKTLQEVYVNIVDWKTCA 187
            |||.:..||.:.|.:  :....||...:.|||       :|     |.:.|:|:.:.::|.:.|.
Human   120 KVKPSRTIRPLALPSKRQVVAAGTRCSMAGWG-------LTHQGGRLSRVLRELDLQVLDTRMCN 177

  Fly   188 SDEYKYGEIIYDSMVCAYEKKKD--ACQGDSGGPLAV--GNTLVGIVSW-GYACASNLLPGVYSD 247
            :..:..|. :..||||.....||  .|:|||||||..  |..|..::|: ...|.....|.|.:.
Human   178 NSRFWNGS-LSPSMVCLAADSKDQAPCKGDSGGPLVCGKGRVLARVLSFSSRVCTDIFKPPVATA 241

  Fly   248 VPALRKWI 255
            |.....||
Human   242 VAPYVSWI 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
thetaTry	NP_523693.1	Tryp_SPc	34..255	CDD:214473	70/233 (30%)
GZMM	NP_005308.2	Tryp_SPc	26..252	CDD:238113	72/234 (31%)