Protein Alignment thetaTry and GZMK

DIOPT Version :10

• Sequence 1: NP_523693.1
• Gene: thetaTry / 36218
• FlyBaseID: FBgn0011555
• Length: 262
• Species: Drosophila melanogaster
• Sequence 2: NP_002095.1
• Gene: GZMK / 3003
• HGNCID: 4711
• Length: 264
• Species: Homo sapiens
• Alignment Length: 238
• Identity: 74/238 - (31%)
• Similarity: 113/238 - (47%)
• Gaps: 46/238 - (19%)

  Fly    35 IVGGEDTTIGAHPYQVSLQTKSGSHFCGGSLINEDTVVTAAHCLVGRKVSKVFVRLGSTLYNEGG 99
            |:||::.:..:.|:..|:| ..|.|.|||.||:...|:|||||           :...|......
Human    27 IIGGKEVSPHSRPFMASIQ-YGGHHVCGGVLIDPQWVLTAAHC-----------QYRFTKGQSPT 79

  Fly   100 IVVAVRELAYNEDYNSKTMEY----------------DVGILKLDEKVKETENIRYIELATETP- 147
            :|:....|:.|| .:.:|:|.                |:.::||....|..::::.:.:.::|.
Human    80 VVLGAHSLSKNE-ASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHIRSKTSL 143

  Fly   148 PTGTTAVVTGWGSKCYFWCMTLP------KTLQEVYVNIVDWKTCASDEYKYGE-IIYDSMVCAY 205
            .:||...|||||:       |.|      .||:||.|.::..|.|.|..|..|: .|...||||.
Human   144 RSGTKCKVTGWGA-------TDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCAG 201

  Fly   206 EKK--KDACQGDSGGPLAVGNTLVGIVSWGYACASNLLPGVYS 246
            :.|  ||:|:|||||||........|||.|:.|.....||:|:
Human   202 DAKGQKDSCKGDSGGPLICKGVFHAIVSGGHECGVATKPGIYT 244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
thetaTry	NP_523693.1	Tryp_SPc	34..255	CDD:214473	74/238 (31%)
GZMK	NP_002095.1	Tryp_SPc	27..257	CDD:238113	74/238 (31%)