Protein Alignment thetaTry and GZMA

DIOPT Version :10

• Sequence 1: NP_523693.1
• Gene: thetaTry / 36218
• FlyBaseID: FBgn0011555
• Length: 262
• Species: Drosophila melanogaster
• Sequence 2: NP_006135.2
• Gene: GZMA / 3001
• HGNCID: 4708
• Length: 262
• Species: Homo sapiens
• Alignment Length: 226
• Identity: 76/226 - (33%)
• Similarity: 112/226 - (49%)
• Gaps: 24/226 - (10%)

  Fly    34 RIVGGEDTTIGAHPYQV--SLQTKSGSHFCGGSLINEDTVVTAAHCLVGRKVSKVFVRLGSTLYN 96
            :|:||.:.|..:.||.|  ||..|:   .|.|:||.:|.|:|||||.:.:: |:|.:...|....
Human    28 KIIGGNEVTPHSRPYMVLLSLDRKT---ICAGALIAKDWVLTAAHCNLNKR-SQVILGAHSITRE 88

  Fly    97 E--GGIVVAVRELAYNEDYNSKTMEYDVGILKLDEKVKETENIRYIEL---ATETPPTGTTAVVT 156
            |  ..|::..:|..| ..|:..|.|.|:.:|:|.||.|..:.:..:.|   ..:..| ||...|.
Human    89 EPTKQIMLVKKEFPY-PCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKP-GTMCQVA 151

  Fly   157 GWG--SKCYFWCMTLPKTLQEVYVNIVDWKTCAS-DEYKYGEIIYDSMVCAYEKK--KDACQGDS 216
            |||  .....|    ..||:||.:.|:|.|.|.. :.|.:..:|..:||||...:  :|:|.|||
Human   152 GWGRTHNSASW----SDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDS 212

  Fly   217 GGPLAVGNTLVGIVSWGY--ACASNLLPGVY 245
            |.||.......|:.|:|.  .|.....||||
Human   213 GSPLLCEGVFRGVTSFGLENKCGDPRGPGVY 243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
thetaTry	NP_523693.1	Tryp_SPc	34..255	CDD:214473	76/226 (34%)
GZMA	NP_006135.2	Tryp_SPc	29..254	CDD:238113	76/225 (34%)