Protein Alignment thetaTry and F7

DIOPT Version :10

• Sequence 1: NP_523693.1
• Gene: thetaTry / 36218
• FlyBaseID: FBgn0011555
• Length: 262
• Species: Drosophila melanogaster
• Sequence 2: XP_011535776.2
• Gene: F7 / 2155
• HGNCID: 3544
• Length: 495
• Species: Homo sapiens
• Alignment Length: 290
• Identity: 82/290 - (28%)
• Similarity: 124/290 - (42%)
• Gaps: 68/290 - (23%)

  Fly    11 LAVGSACAGTVGVSNG--------DPFEREGRIVGGEDTTIGAHPYQVSLQTKSGSHFCGGSLIN 67
            ||.|.:|..||....|        :..:.:||||||:....|..|:||.|.. :|:..|||:|||
Human   210 LADGVSCTPTVEYPCGKIPILEKRNASKPQGRIVGGKVCPKGECPWQVLLLV-NGAQLCGGTLIN 273

  Fly    68 EDTVVTAAHCLVGRKVSKVFVRLGSTLYNEGGIVVAVRELAYNE---DYNSK------------- 116
            ...||:||||.             ..:.|...::..:.|...:|   |..|:
Human   274 TIWVVSAAHCF-------------DKIKNWRNLIAVLGEHDLSEHDGDEQSRRVAQVIIPSTYVP 325

  Fly   117 -TMEYDVGILKLDEKVKETENIRYIELATETPPTGTTA-----VVTGWG-------SKCYFWCMT 168
             |..:|:.:|:|.:.|..|:::..:.|...|....|.|     :|:|||       :......:.
Human   326 GTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATALELMVLN 390

  Fly   169 LPKTLQEVYVNIVDWKTCASDEYKYGEI--IYDSMVCA--YEKKKDACQGDSGGPLAVGNT---- 225
            :|:.:.:         .|.....|.|:.  |.:.|.||  .:..||:|:||||||.|....
Human   391 VPRLMTQ---------DCLQQSRKVGDSPNITEYMFCAGYSDGSKDSCKGDSGGPHATHYRGTWY 446

  Fly   226 LVGIVSWGYACASNLLPGVYSDVPALRKWI 255
            |.||||||..||:....|||:.|....:|:
Human   447 LTGIVSWGQGCATVGHFGVYTRVSQYIEWL 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
thetaTry	NP_523693.1	Tryp_SPc	34..255	CDD:214473	73/257 (28%)
F7	XP_011535776.2	GLA	36..97	CDD:214503
		EGF_CA	99..135	CDD:238011
		FXa_inhibition	180..216	CDD:464251	3/5 (60%)
		Tryp_SPc	242..478	CDD:238113	73/258 (28%)