Protein Alignment thetaTry and CFD

DIOPT Version :10

• Sequence 1: NP_523693.1
• Gene: thetaTry / 36218
• FlyBaseID: FBgn0011555
• Length: 262
• Species: Drosophila melanogaster
• Sequence 2: NP_001304264.1
• Gene: CFD / 1675
• HGNCID: 2771
• Length: 260
• Species: Homo sapiens
• Alignment Length: 269
• Identity: 86/269 - (31%)
• Similarity: 130/269 - (48%)
• Gaps: 28/269 - (10%)

  Fly     1 MHRLVVLLVCLAVGSACAGTVGVSNGDPFEREGRIVGGEDTTIGAHPYQVSLQTKSGSHFCGGSL 65
            ||....|.|.:.:|:|..|....:...|  ..|||:||.:....|.||..|:|. :|:|.|||.|
Human     1 MHSWERLAVLVLLGAAACGEEAWAWAAP--PRGRILGGREAEAHARPYMASVQL-NGAHLCGGVL 62

  Fly    66 INEDTVVTAAHCLVGRKVSKVFVRLGS----------TLYNEGGIVVAVRELAYNEDYNSKTMEY 120
            :.|..|::|||||......||.|.||:          .||:       |.....:.|....|:::
Human    63 VAEQWVLSAAHCLEDAADGKVQVLLGAHSLSQPEPSKRLYD-------VLRAVPHPDSQPDTIDH 120

  Fly   121 DVGILKLDEKVKETENIR---YIELATETPPTGTTAVVTGWGSKCYFWCMTLPKTLQEVYVNIVD 182
            |:.:|:|.||......:|   :..:..:..| ||...|.|||...:  ....|.:||.|.:.::|
Human   121 DLLLLQLSEKATLGPAVRPLPWQRVDRDVAP-GTLCDVAGWGIVNH--AGRRPDSLQHVLLPVLD 182

  Fly   183 WKTCASDEYKYGEIIYDSMVCAYEKKKDACQGDSGGPLAVGNTLVGIVSWG-YACASNLLPGVYS 246
            ..||....:..|.|. :.::||...::|:|:|||||||..|..|.|:|:.| ..|.:...||:|:
Human   183 RATCNRRTHHDGAIT-ERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYT 246

  Fly   247 DVPALRKWI 255
            .|.:...||
Human   247 RVASYAAWI 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
thetaTry	NP_523693.1	Tryp_SPc	34..255	CDD:214473	75/234 (32%)
CFD	NP_001304264.1	Tryp_SPc	33..258	CDD:238113	76/235 (32%)