Protein Alignment thetaTry and Cfd

DIOPT Version :10

• Sequence 1: NP_523693.1
• Gene: thetaTry / 36218
• FlyBaseID: FBgn0011555
• Length: 262
• Species: Drosophila melanogaster
• Sequence 2: NP_038487.1
• Gene: Cfd / 11537
• MGIID: 87931
• Length: 259
• Species: Mus musculus
• Alignment Length: 277
• Identity: 84/277 - (30%)
• Similarity: 131/277 - (47%)
• Gaps: 46/277 - (16%)

  Fly     1 MHRLVVLLVCLAVGSA-CAGTVGVSNGDPFEREGRIVGGEDTTIGAHPYQVSLQTKSGSHFCGGS 64
            ||..|..:..:.:|:| ||.          :..|||:||::....|.||..|:|. :|:|.|||:
Mouse     1 MHSSVYFVALVILGAAVCAA----------QPRGRILGGQEAAAHARPYMASVQV-NGTHVCGGT 54

  Fly    65 LINEDTVVTAAHCLVG-RKVSKVFVRLGSTLYNEGGIVVAVRELAYNEDY--------------- 113
            |::|..|::||||:.| .....|.|.||:            ..|:..|.|
Mouse    55 LLDEQWVLSAAHCMDGVTDDDSVQVLLGA------------HSLSAPEPYKRWYDVQSVVPHPGS 107

  Fly   114 NSKTMEYDVGILKLDEKVKETENIRYIELATETPPT--GTTAVVTGWGSKCYFWCMTLPKTLQEV 176
            ...::|.|:.:.||.:......::|.:.|..|....  ||...|.|||...:  ....|..|.::
Mouse   108 RPDSLEDDLILFKLSQNASLGPHVRPLPLQYEDKEVEPGTLCDVAGWGVVTH--AGRRPDVLHQL 170

  Fly   177 YVNIVDWKTCASDEYKYGEIIYDSMVCAYEKKKDACQGDSGGPLAVGNTLVGIVSWG-YACASNL 240
            .|:|::..||....|..| ::..:|:||...::|.|:||||.||..|:.:.|:|:|| ..|.:..
Mouse   171 RVSIMNRTTCNLRTYHDG-VVTINMMCAESNRRDTCRGDSGSPLVCGDAVEGVVTWGSRVCGNGK 234

  Fly   241 LPGVYSDVPALRKWILN 257
            .||||:.|.:.|.||.|
Mouse   235 KPGVYTRVSSYRMWIEN 251

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
thetaTry	NP_523693.1	Tryp_SPc	34..255	CDD:214473	73/239 (31%)
Cfd	NP_038487.1	Tryp_SPc	26..252	CDD:238113	75/242 (31%)
		Self-inhibitor loop. /evidence=ECO:0000250|UniProtKB:P00746	224..228		2/3 (67%)