Protein Alignment thetaTry and KLK8

DIOPT Version :10

• Sequence 1: NP_523693.1
• Gene: thetaTry / 36218
• FlyBaseID: FBgn0011555
• Length: 262
• Species: Drosophila melanogaster
• Sequence 2: NP_653088.1
• Gene: KLK8 / 11202
• HGNCID: 6369
• Length: 305
• Species: Homo sapiens
• Alignment Length: 243
• Identity: 82/243 - (33%)
• Similarity: 116/243 - (47%)
• Gaps: 37/243 - (15%)

  Fly    31 REGRIVGGEDTTIGAHPYQVSLQTKSGSHFCGGSLINEDTVVTAAHCLVGRKVSKVFVRLGS-TL 94
            :|.:::||.:....:.|:|.:| .:.....|||.|:..:.|:|||||    |..|..||||. :|
Human    74 QEDKVLGGHECQPHSQPWQAAL-FQGQQLLCGGVLVGGNWVLTAAHC----KKPKYTVRLGDHSL 133

  Fly    95 YNEGG------IVVAVRELAYN----EDYNSKTMEYDVGILKLDEKVKETENIRYIELATETPPT 149
            .|:.|      :|.::....||    ||:|     :|:.:|:|.::......::.|.||......
Human   134 QNKDGPEQEIPVVQSIPHPCYNSSDVEDHN-----HDLMLLQLRDQASLGSKVKPISLADHCTQP 193

  Fly   150 GTTAVVTGWGSKCYFWCMTLPK-----TLQEVYVNIVDWKTCASDEYKYGEIIYDSMVCAYEKK- 208
            |....|:|||:      :|.|:     ||....|.|...|.|   |..|...|.|.||||...|
Human   194 GQKCTVSGWGT------VTSPRENFPDTLNCAEVKIFPQKKC---EDAYPGQITDGMVCAGSSKG 249

  Fly   209 KDACQGDSGGPLAVGNTLVGIVSWGY-ACASNLLPGVYSDVPALRKWI 255
            .|.|||||||||.....|.||.|||. .|..:..||||:::.....||
Human   250 ADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWI 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
thetaTry	NP_523693.1	Tryp_SPc	34..255	CDD:214473	79/238 (33%)
KLK8	NP_653088.1	Tryp_SPc	77..297	CDD:214473	79/238 (33%)