Protein Alignment etaTry and KLK14

DIOPT Version :10

• Sequence 1: NP_523692.1
• Gene: etaTry / 36217
• FlyBaseID: FBgn0011554
• Length: 262
• Species: Drosophila melanogaster
• Sequence 2: NP_071329.3
• Gene: KLK14 / 43847
• HGNCID: 6362
• Length: 251
• Species: Homo sapiens
• Alignment Length: 262
• Identity: 97/262 - (37%)
• Similarity: 131/262 - (50%)
• Gaps: 36/262 - (13%)

  Fly     8 ILAVLFLLGIYAVSAQSD-GRIVGG----ADTSSYYTKYVVQLRRRSSSSSSYAQTCGGCILDAV 67
            :|..|.:|.|....:|.| .:|:||    ..:..:....:...|||.        .|||.:|...
Human     4 LLTALQVLAIAMTQSQEDENKIIGGHTCTRSSQPWQAALLAGPRRRF--------LCGGALLSGQ 60

  Fly    68 TIATAAHCVYNREAENFLVVA-GDDS--RGGMNGVVVRVSKLIPHELYNSSTMDNDIALVVVDPP 129
            .:.|||||     ....|.|| |..:  |......|:||.:.:.|..|||.|.|||:.|:.:..|
Human    61 WVITAAHC-----GRPILQVALGKHNLRRWEATQQVLRVVRQVTHPNYNSRTHDNDLMLLQLQQP 120

  Fly   130 LPLDSFSTMEAIEIASEQPAVGVQATISGWGYTKENGLSSD------QLQQVKVPIVDSEKCQEA 188
            ..:.  ..:..||:.....:.|....:||||     .:||.      .||.|.:.|...|.||:|
Human   121 ARIG--RAVRPIEVTQACASPGTSCRVSGWG-----TISSPIARYPASLQCVNINISPDEVCQKA 178

  Fly   189 YYWRPISEGMLCAGLSEGGKDACQGDSGGPLVVANKLAGIVSWG-EGCARPNYPGVYANVAYYKD 252
            |. |.|:.||:|||:.:||||:||||||||||...:|.|:|||| |.||.|.|||||.|:..|:.
Human   179 YP-RTITPGMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYPGVYTNLCKYRS 242

  Fly   253 WI 254
            ||
Human   243 WI 244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
etaTry	NP_523692.1	Tryp_SPc	27..254	CDD:214473	89/240 (37%)
KLK14	NP_071329.3	Tryp_SPc	25..247	CDD:238113	91/241 (38%)