Protein Alignment etaTry and KLK2

DIOPT Version :10

• Sequence 1: NP_523692.1
• Gene: etaTry / 36217
• FlyBaseID: FBgn0011554
• Length: 262
• Species: Drosophila melanogaster
• Sequence 2: NP_005542.1
• Gene: KLK2 / 3817
• HGNCID: 6363
• Length: 261
• Species: Homo sapiens
• Alignment Length: 267
• Identity: 87/267 - (32%)
• Similarity: 127/267 - (47%)
• Gaps: 38/267 - (14%)

  Fly     8 ILAVLFLLGIYAVSAQSDGRIVGGADTSSYYTKYVVQLRRRSSSSSSYAQTCGGCILDAVTIATA 72
            :|::...:|..........|||||.:...:...:.|.:     .|..:|. |||.::....:.||
Human     5 VLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAV-----YSHGWAH-CGGVLVHPQWVLTA 63

  Fly    73 AHCVYNREAENFLVVAG-------DDSRGGMNGVVVRVSKLIPHELYNSSTM-----------DN 119
            |||:    .:|..|..|       :|:     |..|.||...||.|||.|.:           .:
Human    64 AHCL----KKNSQVWLGRHNLFEPEDT-----GQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSH 119

  Fly   120 DIALVVVDPPLPLDSFSTMEAIEIASEQPAVGVQATISGWGYTK-ENGLSSDQLQQVKVPIVDSE 183
            |:.|:.:..|..:.  ..::.:.:.:::||:|.....||||..: |..|....||.|.:.::.::
Human   120 DLMLLRLSEPAKIT--DVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSND 182

  Fly   184 KCQEAYYWRPISEGMLCAGLSEGGKDACQGDSGGPLVVANKLAGIVSWG-EGCARPNYPGVYANV 247
            .|..||. ..::|.||||||..||||.|.||||||||....|.||.||| |.||.|..|.||..|
Human   183 MCARAYS-EKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKV 246

  Fly   248 AYYKDWI 254
            .:|:.||
Human   247 VHYRKWI 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
etaTry	NP_523692.1	Tryp_SPc	27..254	CDD:214473	83/246 (34%)
KLK2	NP_005542.1	Tryp_SPc	25..256	CDD:238113	84/247 (34%)