Protein Alignment etaTry and KLK1

DIOPT Version :10

• Sequence 1: NP_523692.1
• Gene: etaTry / 36217
• FlyBaseID: FBgn0011554
• Length: 262
• Species: Drosophila melanogaster
• Sequence 2: NP_002248.1
• Gene: KLK1 / 3816
• HGNCID: 6357
• Length: 262
• Species: Homo sapiens
• Alignment Length: 266
• Identity: 83/266 - (31%)
• Similarity: 128/266 - (48%)
• Gaps: 35/266 - (13%)

  Fly     8 ILAVLFLLGIYAVSAQSDGRIVGGADTSSYYTKYVVQLRRRSSSSSSYAQTCGGCILDAVTIATA 72
            :|.:...||....:.....|||||.:...:...:...|...|:..      |||.::....:.||
Human     5 VLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQ------CGGILVHRQWVLTA 63

  Fly    73 AHCVYNREAENFLVVAG-----DDSRGGMNGVVVRVSKLIPHELYNSSTMDN-----------DI 121
            |||:    ::|:.:..|     ||..   ....|.||:..||..:|.|.::|           |:
Human    64 AHCI----SDNYQLWLGRHNLFDDEN---TAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDL 121

  Fly   122 ALVVVDPPLPLDSFS-TMEAIEIASEQPAVGVQATISGWGYTK-ENGLSSDQLQQVKVPIVDSEK 184
            .|:.:..  |.|:.: .::.:|:.:|:|.||.....||||..: ||....|.||.|.:.|:.:::
Human   122 MLLRLTE--PADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDE 184

  Fly   185 CQEAYYWRPISEGMLCAGLSEGGKDACQGDSGGPLVVANKLAGIVSWG-EGCARPNYPGVYANVA 248
            |::|:. :.:::.|||.|..|||||.|.|||||||:....|.|:.||| ..|..||.|.|...|.
Human   185 CKKAHV-QKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAVRVL 248

  Fly   249 YYKDWI 254
            .|..||
Human   249 SYVKWI 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
etaTry	NP_523692.1	Tryp_SPc	27..254	CDD:214473	78/245 (32%)
KLK1	NP_002248.1	Tryp_SPc	25..257	CDD:238113	79/246 (32%)