Protein Alignment etaTry and PRSS53

DIOPT Version :10

• Sequence 1: NP_523692.1
• Gene: etaTry / 36217
• FlyBaseID: FBgn0011554
• Length: 262
• Species: Drosophila melanogaster
• Sequence 2: XP_011544118.1
• Gene: PRSS53 / 339105
• HGNCID: 34407
• Length: 623
• Species: Homo sapiens
• Alignment Length: 268
• Identity: 61/268 - (22%)
• Similarity: 94/268 - (35%)
• Gaps: 80/268 - (29%)

  Fly    56 AQTCGGCILDAVTIATAAHCVYN---REAENFLVVAGDDSRGGMN--GVVVRVSKLIPHELYNSS 115
            |..|.|.::....:.|||||...   .|..::.||.|...|.|::  ...|.|:.|.....||..
Human    59 AHICSGSLVADTWVLTAAHCFEKAAATELNSWSVVLGSLQREGLSPGAEEVGVAALQLPRAYNHY 123

  Fly   116 TMDNDIALVVVDPP---LPLDSFSTMEAIEIASEQPA----VGVQATISGWGYTKENG------- 166
            :..:|:||:.:..|   .||           ...|||    .|.....:||.....:|
Human   124 SQGSDLALLQLAHPTTHTPL-----------CLPQPAHRFPFGASCWATGWDQDTSDGKCWPRLK 177

  Fly   167 ------------------------LSSDQ--------------LQQVKVPIVDSEKC-------Q 186
                                    |...|              |:.:::.::....|       .
Human   178 LGEALCLPSVTVSAPNCPGFQSPLLPRSQTLAPAPSLSPAPGTLRNLRLRLISRPTCNCIYNQLH 242

  Fly   187 EAYYWRPISEGMLCAGLSEGGKDACQGDSGGPLVVANK-----LAGIVSWGEGCARPNYPGVYAN 246
            :.:...|...||||.|...|.:..||||||||::....     .|||:|:...||:.:.|.:..|
Human   243 QRHLSNPARPGMLCGGPQPGVQGPCQGDSGGPVLCLEPDGHWVQAGIISFASSCAQEDAPVLLTN 307

  Fly   247 VAYYKDWI 254
            .|.:..|:
Human   308 TAAHSSWL 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
etaTry	NP_523692.1	Tryp_SPc	27..254	CDD:214473	60/266 (23%)
PRSS53	XP_011544118.1	Tryp_SPc	42..316	CDD:238113	61/268 (23%)
		Tryp_SPc	359..>512	CDD:473915