DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment etaTry and C1r

DIOPT Version :9

Sequence 1:	NP_523692.1	Gene:	etaTry / 36217	FlyBaseID:	FBgn0011554	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_001128027.1	Gene:	C1r / 312705	RGDID:	1309091	Length:	707	Species:	Rattus norvegicus

Alignment Length:	266	Identity:	80/266 - (30%)
Similarity:	115/266 - (43%)	Gaps:	61/266 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 RIVGG--ADTSSYYTKYVVQLRRRSSSSSSYAQTCGGCILDAVTIATAAHCVYNRE--AENFLVV 87
            ||:||  |:..::..:....:..|.          ||.:|....|.||||.:|.:|  .||.:.|
  Rat   463 RIIGGQKANPGNFPWQAFTNIHGRG----------GGALLGDRWILTAAHTIYPKEHNKENNVNV 517

  Fly    88 AGDDSRGGMNGVVVR------VSKLIPHELYNSSTMDN---DIAL------VVVDP---PLPLDS 134
            :.|...|..|...::      |.::|.|..|.....:|   ||||      |.:.|   |:.|..
  Rat   518 SKDVFLGHTNVEEIKKLGHHPVRRVIIHPDYRQDEPNNFEGDIALLELENSVTLGPNLLPICLPD 582

  Fly   135 FSTMEAIEIASEQPAVGVQATISGWGYTKENGLSSDQLQQVKVPIVDSEKCQEAYYW-------R 192
            ..|.      .::..:|.   :||:|.|::.  .:..|:.|::||.|.|.||.   |       .
  Rat   583 NETF------YDKDLMGY---VSGFGITEDK--IAFNLRFVRLPIADREACQR---WLRTKNSND 633

  Fly   193 PISEGMLCAGLSEGGKDACQGDSGGPLVVANK------LAGIVSWGEGCARPNYPGVYANVAYYK 251
            ..|:.|.|:|......|||||||||...|.::      ..||||||.||.. .| |.|..:..|.
  Rat   634 VFSQNMFCSGDPTLKHDACQGDSGGVFAVRDRSRDIWVATGIVSWGIGCGE-GY-GFYTKLLNYV 696

  Fly   252 DWIAKQ 257
            |||.|:
  Rat   697 DWIKKE 702

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
etaTry	NP_523692.1	Tryp_SPc	27..254	CDD:214473	77/261 (30%)
etaTry	NP_523692.1	Tryp_SPc	28..257	CDD:238113	78/263 (30%)
C1r	NP_001128027.1	CUB	27..138	CDD:214483
		FXa_inhibition	161..189	CDD:291342
		CUB	195..302	CDD:278839
		Sushi	309..371	CDD:278512
		Sushi	376..447	CDD:278512
		Tryp_SPc	463..699	CDD:214473	77/261 (30%)
		Tryp_SPc	464..701	CDD:238113	78/262 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000