Protein Alignment etaTry and HGFAC

DIOPT Version :10

• Sequence 1: NP_523692.1
• Gene: etaTry / 36217
• FlyBaseID: FBgn0011554
• Length: 262
• Species: Drosophila melanogaster
• Sequence 2: NP_001284368.1
• Gene: HGFAC / 3083
• HGNCID: 4894
• Length: 662
• Species: Homo sapiens
• Alignment Length: 265
• Identity: 86/265 - (32%)
• Similarity: 115/265 - (43%)
• Gaps: 67/265 - (25%)

  Fly    27 RIVGGADTSSYYTKYVVQLRRRSSSSSSYA---------QTCGGCILDAVTIATAAHCV-YNREA 81
            ||:||:                ||...|:.         ..|.|.::....:.:||||. ::...
Human   414 RIIGGS----------------SSLPGSHPWLAAIYIGDSFCAGSLVHTCWVVSAAHCFSHSPPR 462

  Fly    82 ENFLVVAGDDSRGGMNGV--VVRVSKLIPHELYN-SSTMDNDIALV--------------VVDP- 128
            ::..||.|.........|  ...:.|.||:.||: .:..|:|:.|:              .|.|
Human   463 DSVSVVLGQHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPI 527

  Fly   129 --PLPLDSFSTMEAIEIASEQPAVGVQATISGWGYTKEN--GLSSDQLQQVKVPIVDSEKCQE-A 188
              |.|..:|            || |.:..|:|||:..||  |.|| .|::..||:|...||.. .
Human   528 CLPEPGSTF------------PA-GHKCQIAGWGHLDENVSGYSS-SLREALVPLVADHKCSSPE 578

  Fly   189 YYWRPISEGMLCAGLSEGGKDACQGDSGGPLVVANK----LAGIVSWGEGCARPNYPGVYANVAY 249
            .|...||..|||||..:...|||||||||||.....    |.||:|||:||.|.:.||||..||.
Human   579 VYGADISPNMLCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLHKPGVYTRVAN 643

  Fly   250 YKDWI 254
            |.|||
Human   644 YVDWI 648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
etaTry	NP_523692.1	Tryp_SPc	27..254	CDD:214473	84/263 (32%)
HGFAC	NP_001284368.1	PRK14954	<32..>100	CDD:184918
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	64..102
		FN2	102..148	CDD:128373
		EGF_CA	162..197	CDD:238011
		FN1	200..240	CDD:238018
		EGF_CA	245..278	CDD:238011
		Kringle	286..367	CDD:395005
		Tryp_SPc	415..650	CDD:238113	85/264 (32%)