Protein Alignment etaTry and GZMK

DIOPT Version :10

• Sequence 1: NP_523692.1
• Gene: etaTry / 36217
• FlyBaseID: FBgn0011554
• Length: 262
• Species: Drosophila melanogaster
• Sequence 2: NP_002095.1
• Gene: GZMK / 3003
• HGNCID: 4711
• Length: 264
• Species: Homo sapiens
• Alignment Length: 257
• Identity: 77/257 - (29%)
• Similarity: 122/257 - (47%)
• Gaps: 22/257 - (8%)

  Fly    10 AVLFLL-GIYAVSAQSDGRIVGGADTSSYYTKYVVQLRRRSSSSSSYA--QTCGGCILDAVTIAT 71
            ::.||: |.|......:..|:||.:.|.:...::        :|..|.  ..|||.::|...:.|
Human     8 SLFFLIVGAYMTHVCFNMEIIGGKEVSPHSRPFM--------ASIQYGGHHVCGGVLIDPQWVLT 64

  Fly    72 AAHCVYN-REAENFLVVAGDD--SRGGMNGVVVRVSKLIPHELYNSSTMDNDIALVVVDPPLPLD 133
            ||||.|. .:.::..||.|..  |:...:...:.:.|.||.....|....|||.||.:.....|:
Human    65 AAHCQYRFTKGQSPTVVLGAHSLSKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLN 129

  Fly   134 SFSTMEAIEIASEQP-AVGVQATISGWGYTKENGL-SSDQLQQVKVPIVDSEKCQEAYYWRP--- 193
            ....|  :.|.|:.. ..|.:..::|||.|..:.| .||.|::|.|.::..:.|....|:..
Human   130 KHVKM--LHIRSKTSLRSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPF 192

  Fly   194 ISEGMLCAGLSEGGKDACQGDSGGPLVVANKLAGIVSWGEGCARPNYPGVYANVA-YYKDWI 254
            |::.|:|||.::|.||:|:|||||||:.......|||.|..|.....||:|..:. .|:.||
Human   193 ITKDMVCAGDAKGQKDSCKGDSGGPLICKGVFHAIVSGGHECGVATKPGIYTLLTKKYQTWI 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
etaTry	NP_523692.1	Tryp_SPc	27..254	CDD:214473	71/237 (30%)
GZMK	NP_002095.1	Tryp_SPc	27..257	CDD:238113	73/238 (31%)