DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment etaTry and PRSS55

DIOPT Version :9

Sequence 1:	NP_523692.1	Gene:	etaTry / 36217	FlyBaseID:	FBgn0011554	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_940866.2	Gene:	PRSS55 / 203074	HGNCID:	30824	Length:	352	Species:	Homo sapiens

Alignment Length:	241	Identity:	80/241 - (33%)
Similarity:	122/241 - (50%)	Gaps:	21/241 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 RIVGGADTSSYYTKYVVQLRRRSSSSSSYAQTCGGCILDAVTIATAAHCVYNRE--AENFLVVAG 89
            ||.||.:.......:.|.::.||.      ..|||.||:...|.|||||:|:.|  .|...||.|
Human    67 RITGGMEAEVGEFPWQVSIQARSE------PFCGGSILNKWWILTAAHCLYSEELFPEELSVVLG 125

  Fly    90 DDSRGGMNGVVVRVSKLIPHELYNSSTMDNDIALVVVDPPLPLDSFSTMEAIEIASEQPAVGVQA 154
            .:.....:..:..|:.:|.|:.:..:.|||||||:::..|:.||.......:. ....||...:.
Human   126 TNDLTSPSMEIKEVASIILHKDFKRANMDNDIALLLLASPIKLDDLKVPICLP-TQPGPATWREC 189

  Fly   155 TISGWGYTK---ENGLSSDQLQQVKVPIVDSEKCQEAYYWRPISEGMLCAGLSEGGKDACQGDSG 216
            .::|||.|.   :|.:.:| |.:..:.|:|.|:|.:.:  ..:::.|||||......|||:||||
Human   190 WVAGWGQTNAADKNSVKTD-LMKAPMVIMDWEECSKMF--PKLTKNMLCAGYKNESYDACKGDSG 251

  Fly   217 GPLVVANK------LAGIVSWGEGCARPNYPGVYANVAYYKDWIAK 256
            ||||...:      ..||:|||:.|...|.||:|.::..|..||.|
Human   252 GPLVCTPEPGEKWYQVGIISWGKSCGEKNTPGIYTSLVNYNLWIEK 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
etaTry	NP_523692.1	Tryp_SPc	27..254	CDD:214473	77/237 (32%)
etaTry	NP_523692.1	Tryp_SPc	28..257	CDD:238113	79/240 (33%)
PRSS55	NP_940866.2	Tryp_SPc	67..295	CDD:214473	77/237 (32%)
		Tryp_SPc	68..298	CDD:238113	79/240 (33%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	308..330
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910