DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment etaTry and PRSS36

DIOPT Version :9

Sequence 1:	NP_523692.1	Gene:	etaTry / 36217	FlyBaseID:	FBgn0011554	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_775773.2	Gene:	PRSS36 / 146547	HGNCID:	26906	Length:	855	Species:	Homo sapiens

Alignment Length:	259	Identity:	81/259 - (31%)
Similarity:	118/259 - (45%)	Gaps:	35/259 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 QSDGRIVGGADTSSYYTKYVVQLRRRSSSSSSYAQTCGGCILDAVTIATAAHCVYN----REAEN 83
            :...|||||::.......:.|.|....      ...|||.::....:.:||||...    ..|..
Human    42 EPSARIVGGSNAQPGTWPWQVSLHHGG------GHICGGSLIAPSWVLSAAHCFMTNGTLEPAAE 100

  Fly    84 FLVVAGDDSRGG-MNGVVVR-VSKLIPHELYNSSTMDNDIALVVVDPPLPLDSFSTMEAIEIASE 146
            :.|:.|..|:.| ::|...| |:.::....|:...:..|:||:.:..|..|........:..||.
Human   101 WSVLLGVHSQDGPLDGAHTRAVAAIVVPANYSQVELGADLALLRLASPASLGPAVWPVCLPRASH 165

  Fly   147 QPAVGVQATISGWGYTKENGLSSDQ------LQQVKVPIVDSEKCQEAYYWRP--------ISEG 197
            :...|.....:|||..:|    :|.      ||:|::.::....|| ..|.:|        |..|
Human   166 RFVHGTACWATGWGDVQE----ADPLPLPWVLQEVELRLLGEATCQ-CLYSQPGPFNLTLQILPG 225

  Fly   198 MLCAGLSEGGKDACQGDSGGPLVVANK----LAGIVSWGEGCARPNYPGVYANVAYYKDWIAKQ 257
            |||||..||.:|.||||||||||....    .|||.|:|.||.|.|.|||:..||.|:.||.:|
Human   226 MLCAGYPEGRRDTCQGDSGGPLVCEEGGRWFQAGITSFGFGCGRRNRPGVFTAVATYEAWIREQ 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
etaTry	NP_523692.1	Tryp_SPc	27..254	CDD:214473	78/250 (31%)
etaTry	NP_523692.1	Tryp_SPc	28..257	CDD:238113	79/252 (31%)
PRSS36	NP_775773.2	Tryp_SPc	46..286	CDD:214473	78/250 (31%)
		Tryp_SPc	47..289	CDD:238113	79/252 (31%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	292..316
		Tryp_SPc	330..538	CDD:304450
		Tryp_SPc	601..783	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010