Protein Alignment zetaTry and KLK4

DIOPT Version :9

• Sequence 1: NP_523691.1
• Gene: zetaTry / 36216
• FlyBaseID: FBgn0011556
• Length: 280
• Species: Drosophila melanogaster
• Sequence 2: NP_004908.4
• Gene: KLK4 / 9622
• HGNCID: 6365
• Length: 254
• Species: Homo sapiens
• Alignment Length: 287
• Identity: 80/287 - (27%)
• Similarity: 121/287 - (42%)
• Gaps: 65/287 - (22%)

  Fly     5 WIVGLLAFLVSLVALTQGLPLLEDLDEKSVPDGRIVGGYATDIA--------QVPYQISLRYKGI 61
            |.:|.|...|:                     |.:|.|..:.|.        ..|:|.:|
Human    10 WFLGYLILGVA---------------------GSLVSGSCSQIINGEDCSPHSQPWQAAL----- 48

  Fly    62 TTPENPFRHRCGGSIFNETTIVTAAHCVIGTVASQYKVVAG-----TNFQTGSDGVITNVKEIVM 121
             ..||..  .|.|.:.:...:::||||    ..:.|.:..|     .:.:.||..|..::.  |.
Human    49 -VMENEL--FCSGVLVHPQWVLSAAHC----FQNSYTIGLGLHSLEADQEPGSQMVEASLS--VR 104

  Fly   122 HEGYYSGAAYNNDIAILFVDPPLPLNNFTIKAIKLALEQPIEGTVSKVSGWGTTSPGGYSSNQLL 186
            |. .|:.....||:.::.:|..:..:: ||::|.:|.:.|..|....|||||..: .|.....|.
Human   105 HP-EYNRPLLANDLMLIKLDESVSESD-TIRSISIASQCPTAGNSCLVSGWGLLA-NGRMPTVLQ 166

  Fly   187 AVDVPIVSNELCDQDYEDFGDETYRITSAMLCAGKRGVGG---ADACQGDSGGPLAVRDELYGVV 248
            .|:|.:||.|:|.:.|    |..|.  .:|.|||    ||   .|:|.|||||||.....|.|:|
Human   167 CVNVSVVSEEVCSKLY----DPLYH--PSMFCAG----GGQDQKDSCNGDSGGPLICNGYLQGLV 221

  Fly   249 SWGNS-CALPNYPGVYANVAYLRPWID 274
            |:|.: |.....||||.|:.....||:
Human   222 SFGKAPCGQVGVPGVYTNLCKFTEWIE 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
zetaTry	NP_523691.1	Tryp_SPc	38..273	CDD:214473	73/251 (29%)
		Tryp_SPc	39..276	CDD:238113	75/253 (30%)
KLK4	NP_004908.4	Tryp_SPc	31..250	CDD:238113	73/245 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920