DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment zetaTry and TMPRSS11D

DIOPT Version :9

Sequence 1:	NP_523691.1	Gene:	zetaTry / 36216	FlyBaseID:	FBgn0011556	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	NP_004253.1	Gene:	TMPRSS11D / 9407	HGNCID:	24059	Length:	418	Species:	Homo sapiens

Alignment Length:	283	Identity:	88/283 - (31%)
Similarity:	134/283 - (47%)	Gaps:	46/283 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SSSWIVGLLAFLVSLVALTQGLPLLEDLDEKSVPDGRIVGGYATDIAQVPYQISLRYKGITTPEN 66
            :::|::........|:.|:               :.||:||...:....|:|:|||...
Human   165 AANWLINECGAGPDLITLS---------------EQRILGGTEAEEGSWPWQVSLRLNN------ 208

  Fly    67 PFRHRCGGSIFNETTIVTAAHCVIGTVASQYKVVAGTNFQTGSDGVITNVKEIVMHEGYYSGAAY 131
              .|.||||:.|...|:||||| ..:.::....:|.:...|....:...|:.|::|..|.| |.:
Human   209 --AHHCGGSLINNMWILTAAHC-FRSNSNPRDWIATSGISTTFPKLRMRVRNILIHNNYKS-ATH 269

  Fly   132 NNDIAILFVDPPLPLNNFTIK------AIKLALEQPIEGTVSKVSGWGTTSPGGYSSNQLLAVDV 190
            .||||::.::     |:.|..      .:..|.:....|:.:.|:|||.....|::..:|....|
Human   270 ENDIALVRLE-----NSVTFTKDIHSVCLPAATQNIPPGSTAYVTGWGAQEYAGHTVPELRQGQV 329

  Fly   191 PIVSNELCDQDYEDFGDETYRITSAMLCAGKRGVGGADACQGDSGGPLAVRDE-----LYGVVSW 250
            .|:||::|:..:...|    .|.|.|||||. ..||.|||||||||||...|.     :.|:|||
Human   330 RIISNDVCNAPHSYNG----AILSGMLCAGV-PQGGVDACQGDSGGPLVQEDSRRLWFIVGIVSW 389

  Fly   251 GNSCALPNYPGVYANVAYLRPWI 273
            |:.|.||:.||||..|.....||
Human   390 GDQCGLPDKPGVYTRVTAYLDWI 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zetaTry	NP_523691.1	Tryp_SPc	38..273	CDD:214473	83/245 (34%)
zetaTry	NP_523691.1	Tryp_SPc	39..276	CDD:238113	84/246 (34%)
TMPRSS11D	NP_004253.1	SEA	48..143	CDD:279699
		Tryp_SPc	186..412	CDD:214473	83/245 (34%)
		Tryp_SPc	187..415	CDD:238113	84/246 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910