DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zetaTry and Prss12

DIOPT Version :9

Sequence 1:	NP_523691.1	Gene:	zetaTry / 36216	FlyBaseID:	FBgn0011556	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	NP_445956.1	Gene:	Prss12 / 85266	RGDID:	69238	Length:	761	Species:	Rattus norvegicus

Alignment Length:	256	Identity:	83/256 - (32%)
Similarity:	122/256 - (47%)	Gaps:	30/256 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 RIVGGYATDIAQVPYQISLRYKGITTPENPFRHRCGGSIFNETTIVTAAHCV--IGTVASQYKVV 100
            ||:||..:.....|:|.|||.|   :.....|..||.::.:...::|||||.  .|..:..|.|.
  Rat   516 RIIGGNNSLRGAWPWQASLRLK---STHGDGRLLCGATLLSSCWVLTAAHCFTRYGNNSRSYAVR 577

  Fly   101 AGTNFQTGSDGVITN--VKEIVMHEGYYSGAAYNNDIAILFV----DPPLPLNNFTIKA-IKLAL 158
            .|.......:|...:  |::||:|..|...:: :.|||::.:    :....|:...:.| :.|..
  Rat   578 VGDYHTLVPEGFEQDIGVQQIVIHRNYRPDSS-DYDIALVRLQGSGEQCARLSTHVLPACLPLWR 641

  Fly   159 EQPIEGTVSK--VSGWGTTSPGGYSSNQLLAVDVPIVSNELCDQDYEDFGDETYRITSAMLCAGK 221
            |:| :.|.|.  ::|||.|  |...|..|....||::....|.:.|:..      .|..|||||.
  Rat   642 ERP-QKTASNCHITGWGDT--GRAYSRTLQQAAVPLLPKRFCKERYKGL------FTGRMLCAGN 697

  Fly   222 -RGVGGADACQGDSGGPLAVR--DE---LYGVVSWGNSCALPNYPGVYANVAYLRPWIDAV 276
             :.....|:|||||||||...  ||   :|||.|||..|.:.:.||||..|....|||.:|
  Rat   698 LQEDNRVDSCQGDSGGPLMCEKPDETWVVYGVTSWGYGCGIKDTPGVYTRVPAFVPWIKSV 758

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zetaTry	NP_523691.1	Tryp_SPc	38..273	CDD:214473	80/251 (32%)
zetaTry	NP_523691.1	Tryp_SPc	39..276	CDD:238113	81/253 (32%)
Prss12	NP_445956.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	26..89
		KR	83..159	CDD:214527
		SR	166..265	CDD:214555
		SRCR	171..266	CDD:278931
		SR	273..372	CDD:214555
		SRCR	278..371	CDD:278931
		SR	386..485	CDD:214555
		SRCR	391..485	CDD:278931
		Zymogen activation region. /evidence=ECO:0000250	505..516		83/256 (32%)
		Tryp_SPc	516..755	CDD:214473	80/251 (32%)
		Tryp_SPc	517..758	CDD:238113	81/253 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910