DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zetaTry and f7

DIOPT Version :9

Sequence 1:	NP_523691.1	Gene:	zetaTry / 36216	FlyBaseID:	FBgn0011556	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	NP_001072819.1	Gene:	f7 / 780280	XenbaseID:	XB-GENE-5787186	Length:	452	Species:	Xenopus tropicalis

Alignment Length:	265	Identity:	83/265 - (31%)
Similarity:	127/265 - (47%)	Gaps:	36/265 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 LPLLEDLDEKSVPDGRIVGGYATDIAQVPYQISLRYKGITTPENPFRHRCGGSIFNETTIVTAAH 87
            :|:|:::::::    |||||......:.|:|..|.|..|..        |||::.....::||||
Frog   200 IPVLKNVNKRA----RIVGGDMCPKGECPWQALLMYNEIFI--------CGGTLIAPNWVITAAH 252

  Fly    88 CVIGTVASQYKVVAGTNFQTGSDGV--ITNVKEIVMHEGYYSGAAYN-NDIAILFVDPPLPLNNF 149
            |:.....::..||.|.:.....:|.  .:.|.:|:|||.||.....| ||||:|.:..|:   |:
Frog   253 CLKPLPENKLTVVLGEHRIGTPEGTEQESKVSKIIMHEHYYGSKTNNDNDIALLKLTTPV---NY 314

  Fly   150 TIKAIKL-------ALEQPIEGTVSKVSGWGTTSPGGYSSNQLLAVDVPIVSNELCDQDYEDFGD 207
            |...:.|       |:::.:....|.|||||.....|.:...|..|.:|.|..:.|.:..:
Frog   315 TDYVVPLCLPEKQFAVQELLSIRYSTVSGWGRLLESGATPELLQRVQLPRVKTQDCIRQTQ---- 375

  Fly   208 ETYRITSAMLCAGKRGVGGADACQGDSGGPLAVRDE----LYGVVSWGNSCALPNYPGVYANVAY 268
              ..|:..|.|||... |..|:|:||||||.|.:.:    |.|:||||..||.....|||..|:.
Frog   376 --MNISQNMFCAGYTD-GSKDSCKGDSGGPHATQYKNTHFLTGIVSWGLGCAKKEKYGVYTRVSR 437

  Fly   269 LRPWI 273
            ...||
Frog   438 YTEWI 442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zetaTry	NP_523691.1	Tryp_SPc	38..273	CDD:214473	79/248 (32%)
zetaTry	NP_523691.1	Tryp_SPc	39..276	CDD:238113	80/249 (32%)
f7	NP_001072819.1	Gla	67..107	CDD:366184
		EGF_CA	108..144	CDD:238011
		FXa_inhibition	153..189	CDD:373209
		Tryp_SPc	212..445	CDD:238113	80/249 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910