DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zetaTry and tmprss9

DIOPT Version :9

Sequence 1:	NP_523691.1	Gene:	zetaTry / 36216	FlyBaseID:	FBgn0011556	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	XP_021325244.1	Gene:	tmprss9 / 562051	ZFINID:	ZDB-GENE-050208-573	Length:	788	Species:	Danio rerio

Alignment Length:	265	Identity:	89/265 - (33%)
Similarity:	129/265 - (48%)	Gaps:	50/265 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 KSVPDGRIVGGYATDIAQVPYQISLRYKGITTPENPFRHRCGGSIFNETTIVTAAHCV-IGTVAS 95
            :.|...|||||..|...:.|:|:|||.:|        ||.||.||.|...:|:||||. :.....
Zfish   225 RPVMSNRIVGGENTRHGEFPWQVSLRLRG--------RHTCGASIVNSRWLVSAAHCFEVENNPK 281

  Fly    96 QYKVVAGTNFQTG--SDGVITNVKEIVMHEGYYSGAAYNNDIAILFVDPPLPLNNFTIKAIKLAL 158
            .:..:.|.|..:|  ::..|.|:|.:|| ...|.....::|:.:|.::.||..:::.
Zfish   282 DWTALVGANQVSGAEAEAFIVNIKSLVM-SPKYDPMTTDSDVTVLELETPLKFSHYV-------- 337

  Fly   159 EQPI----------EGTVSKVSGWGTTSPGGYSS---NQLLAVDVPIVSNELCDQDYEDFGDETY 210
             ||:          .|....|||||..:.  |::   :.|....|.|:.:::|::      ...|
Zfish   338 -QPVCIPSSSHVFTPGQNCIVSGWGALNQ--YTTEVPSTLQKAIVKIIDSKVCNK------SSVY 393

  Fly   211 R--ITSAMLCAGKRGVGGADACQGDSGGPLAV-----RDELYGVVSWGNSCALPNYPGVYANVAY 268
            |  :|..|:|||.. .|..|:||||||||||.     |..|.|:||||..||..|.||||:.|..
Zfish   394 RGALTQNMMCAGFL-QGKVDSCQGDSGGPLACEVAAGRYFLAGIVSWGVGCAQINKPGVYSRVTK 457

  Fly   269 LRPWI 273
            ||.||
Zfish   458 LRNWI 462

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zetaTry	NP_523691.1	Tryp_SPc	38..273	CDD:214473	86/257 (33%)
zetaTry	NP_523691.1	Tryp_SPc	39..276	CDD:238113	87/258 (34%)
tmprss9	XP_021325244.1	SEA	52..146	CDD:307516
		LDLa	185..220	CDD:238060
		Tryp_SPc	232..462	CDD:238113	85/256 (33%)
		LDLa	510..544	CDD:238060
		Tryp_SPc	557..783	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910