DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment zetaTry and zgc:100868

DIOPT Version :9

Sequence 1:	NP_523691.1	Gene:	zetaTry / 36216	FlyBaseID:	FBgn0011556	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	XP_005164187.1	Gene:	zgc:100868 / 554458	ZFINID:	ZDB-GENE-040801-33	Length:	654	Species:	Danio rerio

Alignment Length:	281	Identity:	98/281 - (34%)
Similarity:	138/281 - (49%)	Gaps:	36/281 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 IVGLLAFLVSL-VALTQGLPLLEDLDEKSVPDGRIVGGYATDIAQVPYQISLRYKGITTPENPFR 69
            |||     |:| :||..|.....|:...:..:.|||||....:...|:|:||:..|        .
Zfish     8 IVG-----VALTIALLTGCDAQLDVCGTAPLNSRIVGGQNAPVGAWPWQVSLQRDG--------S 59

  Fly    70 HRCGGSIFNETTIVTAAHCVIGTVASQYKVVAG----TNFQTGSDGVITNVKEIVMHEGYYSGAA 130
            |.||||:.|...|:|||||......:...|..|    .:|::.|  :.:.|..|:.|..|.|...
Zfish    60 HFCGGSLINNQWILTAAHCFPNPSTTGLLVYLGLQKLASFESYS--MSSAVSNIIKHPNYNSDTE 122

  Fly   131 YNNDIAILFVDPPLPLNNFTIKAIKLALEQP--IEGTVSKVSGWGTTSPGGY--SSNQLLAVDVP 191
             :|||.:|.:...:..:|: |:.|.||....  ..||:..::|||.|:.|..  |...|..|.||
Zfish   123 -DNDITLLQLASTVSFSNY-IRPICLAASDSTFFNGTLVWITGWGNTATGVSLPSPGTLQEVQVP 185

  Fly   192 IVSNELCDQDYEDFGDETYRITSAMLCAGKRGVGGADACQGDSGGPLAVRDELY----GVVSWGN 252
            ||.|..|:..|     ...:||..|:|||.. .||.|:||||||||:..:....    |:||:|.
Zfish   186 IVGNRKCNCLY-----GVSKITDNMVCAGLL-QGGKDSCQGDSGGPMVSKQGSVWIQSGIVSFGT 244

  Fly   253 SCALPNYPGVYANVAYLRPWI 273
            .||.||:||||..|:..:.||
Zfish   245 GCAQPNFPGVYTRVSKYQSWI 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zetaTry	NP_523691.1	Tryp_SPc	38..273	CDD:214473	87/246 (35%)
zetaTry	NP_523691.1	Tryp_SPc	39..276	CDD:238113	88/247 (36%)
zgc:100868	XP_005164187.1	Tryp_SPc	36..265	CDD:214473	87/246 (35%)
		Tryp_SPc	37..267	CDD:238113	88/247 (36%)
		Tryp_SPc	331..509	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910