DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zetaTry and prss60.2

DIOPT Version :9

Sequence 1:	NP_523691.1	Gene:	zetaTry / 36216	FlyBaseID:	FBgn0011556	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	NP_001099071.1	Gene:	prss60.2 / 541408	ZFINID:	ZDB-GENE-050320-109	Length:	328	Species:	Danio rerio

Alignment Length:	262	Identity:	91/262 - (34%)
Similarity:	131/262 - (50%)	Gaps:	42/262 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 DGRIVGGYATDIAQVPYQISL---RYKGITTPENPFRHRCGGSIFNETTIVTAAHCVIGTVASQY 97
            :.|||||........|:|:||   ||.|         |.||||:.:...::|||||:.|...|..
Zfish    31 NSRIVGGVNAPEGSWPWQVSLQSPRYGG---------HFCGGSLISSEWVLTAAHCLPGVSESSL 86

  Fly    98 KVVAGTNFQTGSDGVIT--NVKEIVMHEGYYSGAAYNNDIAILFVDPPLPLNNFTIKAIKLALEQ 160
            .|..|...|.|.:...|  ||.:|::|..|.|. ..:||||:|.:...:..|:: |:.:.||.:.
Zfish    87 VVYLGRRTQQGVNTHETSRNVAKIIVHSSYNSN-TNDNDIALLRLSSAVTFNDY-IRPVCLAAQN 149

  Fly   161 PI--EGTVSKVSGWGTTSPG------GYSSNQLLAVDVPIVSNELCDQDYEDFGDETYRITSAML 217
            .:  .||.|.::|||....|      |.....:    :|:|:|:.|:   ...|..|  :|:.|:
Zfish   150 SVYSAGTSSWITGWGDVQAGVNLPAPGILQETM----IPVVANDRCN---AQLGSGT--VTNNMI 205

  Fly   218 CAGKRGVGGADACQGDSGGPLAVRDEL------YGVVSWGNSCALPNYPGVYANVAYLRPWIDAV 276
            ||| ...||.|.||||||||:..|  |      .|:.|||..||.||.||||..|:..:.||.:.
Zfish   206 CAG-LAKGGKDTCQGDSGGPMVTR--LCTVWIQAGITSWGYGCADPNSPGVYTRVSQYQSWISSK 267

  Fly   277 LA 278
            ::
Zfish   268 IS 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zetaTry	NP_523691.1	Tryp_SPc	38..273	CDD:214473	89/253 (35%)
zetaTry	NP_523691.1	Tryp_SPc	39..276	CDD:238113	90/255 (35%)
prss60.2	NP_001099071.1	Tryp_SPc	33..264	CDD:214473	89/253 (35%)
		Tryp_SPc	34..267	CDD:238113	90/255 (35%)
		Somatomedin_B	296..326	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910