DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zetaTry and Tmprss11c

DIOPT Version :9

Sequence 1:	NP_523691.1	Gene:	zetaTry / 36216	FlyBaseID:	FBgn0011556	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	NP_001003979.1	Gene:	Tmprss11c / 408213	RGDID:	1302967	Length:	418	Species:	Rattus norvegicus

Alignment Length:	249	Identity:	93/249 - (37%)
Similarity:	128/249 - (51%)	Gaps:	24/249 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 PDG-RIVGGYATDIAQVPYQISLRYKGITTPENPFRHRCGGSIFNETTIVTAAHCVIGTV-ASQY 97
            |.| ::.||...:..:.|:|.||:...:        ||||.::.:.:.::|||||.:.:. ...:
  Rat   182 PGGHKVAGGQDAEEGEWPWQASLQQNNV--------HRCGATLISNSWLITAAHCFVRSANPKDW 238

  Fly    98 KVVAGTNFQTGSDGVITNVKEIVMHEGYYSGAAYNNDIAILFVDPP-LPLNNFTIKAIKLALEQP 161
            ||..|  |..........||.||:||. ||..|:|||||::.:..| |..||.....:..|.::.
  Rat   239 KVSFG--FLLSKPQAQRAVKSIVIHEN-YSYPAHNNDIAVVRLSSPVLYENNIRRACLPEATQKF 300

  Fly   162 IEGTVSKVSGWGTTSPGGYSSNQLLAVDVPIVSNELCDQDYEDFGDETYRITSAMLCAGKRGVGG 226
            ...:...|:||||....|.|.|.|....|.|:.|:.|:.. :.:|..   ||..|||||.. .|.
  Rat   301 PPNSDVVVTGWGTLKSDGDSPNILQKGRVKIIDNKTCNSG-KAYGGV---ITPGMLCAGFL-EGR 360

  Fly   227 ADACQGDSGGPLAVRDE-----LYGVVSWGNSCALPNYPGVYANVAYLRPWIDA 275
            .|||||||||||...|.     |.|:||||:.|||||.||||..|.:.|.||.:
  Rat   361 VDACQGDSGGPLVSEDSKGIWFLAGIVSWGDECALPNKPGVYTRVTHYRDWISS 414

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zetaTry	NP_523691.1	Tryp_SPc	38..273	CDD:214473	89/241 (37%)
zetaTry	NP_523691.1	Tryp_SPc	39..276	CDD:238113	91/244 (37%)
Tmprss11c	NP_001003979.1	SEA	62..157	CDD:279699
		Tryp_SPc	186..412	CDD:214473	89/241 (37%)
		Tryp_SPc	187..415	CDD:238113	91/244 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920