DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zetaTry and Prss53

DIOPT Version :9

Sequence 1:	NP_523691.1	Gene:	zetaTry / 36216	FlyBaseID:	FBgn0011556	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	NP_001074737.1	Gene:	Prss53 / 330657	MGIID:	2652890	Length:	552	Species:	Mus musculus

Alignment Length:	317	Identity:	80/317 - (25%)
Similarity:	125/317 - (39%)	Gaps:	89/317 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSSSWIVGLLAFLVSLVALTQGLPLLEDLDEKSVP------DGRIVGGYATDIAQVPYQISLRYK 59
            |..||...||  :|..|.:.:||...:....:..|      :|..:.|      :.|:|.|:|.:
Mouse     1 MRQSWRPELL--IVGAVVVIEGLQAAQRACGQRGPGPPEPQEGNTLPG------EWPWQASVRRQ 57

  Fly    60 GITTPENPFRHRCGGSIFNETTIVTAAHC---VIGTVASQYKVVAGTNFQTGSDGVITNVKEIVM 121
            |:        |.|.||:..:|.::|||||   :.....|.:.||.|:                :.
Mouse    58 GV--------HICSGSLVADTWVLTAAHCFEKMATAELSSWSVVLGS----------------LK 98

  Fly   122 HEGYYSGA------------AYN-----NDIAILFVDPPLPLNNFTIKAIKLALEQPIEGTVSKV 169
            .||...||            |||     :|:|:|.:..|      |::. .|.|.||........
Mouse    99 QEGQSPGAEEVGVAALQLPKAYNHYSQGSDLALLQLTHP------TVQT-TLCLPQPTYHFPFGA 156

  Fly   170 SGWGTTSPGGYSSN------QLLAVDVPIVSNELCDQDYEDFGDETYRITS-----AMLCAGKRG 223
            |.|.|    |:..|      .|..:.:.::|...|:..|.....   |:.|     .|||.|.:
Mouse   157 SCWAT----GWDQNTSDVSRTLRNLRLRLISRPTCNCLYNRLHQ---RLLSNPARPGMLCGGAQ- 213

  Fly   224 VGGADACQGDSGGPLAVRDE-----LYGVVSWGNSCALPNYPGVYANVAYLRPWIDA 275
            .|....||||||||:..|:.     ..|::|:.:.||..:.|.:..::|....|:.|
Mouse   214 PGEQGPCQGDSGGPVMCREPDGHWVQVGIISFTSKCAQEDTPVLLTDMAVHSSWLQA 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zetaTry	NP_523691.1	Tryp_SPc	38..273	CDD:214473	67/270 (25%)
zetaTry	NP_523691.1	Tryp_SPc	39..276	CDD:238113	69/273 (25%)
Prss53	NP_001074737.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	27..46		2/18 (11%)
		Tryp_SPc	45..271	CDD:238113	69/271 (25%)
		Tryp_SPc	311..522	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839504
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030