DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zetaTry and plg

DIOPT Version :9

Sequence 1:	NP_523691.1	Gene:	zetaTry / 36216	FlyBaseID:	FBgn0011556	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	NP_958880.2	Gene:	plg / 322691	ZFINID:	ZDB-GENE-030131-1411	Length:	818	Species:	Danio rerio

Alignment Length:	247	Identity:	86/247 - (34%)
Similarity:	121/247 - (48%)	Gaps:	30/247 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 GRIVGGYATDIAQVPYQISLRYKGITTPENPFRHRCGGSIFNETTIVTAAHCVIGTVA-SQYKVV 100
            ||||||..:.....|:|||||.:|..       |.|||::.:...:||||||:..:.: |.||::
Zfish   587 GRIVGGCVSKPHSWPWQISLRTRGKI-------HFCGGTLIDPQWVVTAAHCLERSDSPSAYKIM 644

  Fly   101 AG--TNFQTGSDGVITNVKEIVMHEGYYSGAAYNNDIAILFVDPPLPLNNFTIKAIKLALEQPI- 162
            .|  |...|.|.....:|.:|:      .|.| ..|||:|.:|.|..:|: .:..:.|..:..|
Zfish   645 LGIHTERATESSKQERDVTKII------KGPA-GTDIALLKLDRPALIND-KVSPVCLPEKDYIV 701

  Fly   163 -EGTVSKVSGWGTTSPGGYSSNQLLAVDVPIVSNELCDQDYEDFGDETYRITSAMLCAGKRGVGG 226
             ..|...|:|||.|...| ....|.....|::.|::|::.....|    |:....:|||.. .||
Zfish   702 PSNTECYVTGWGETQDTG-GEGYLKETGFPVIENKVCNRPSFLNG----RVKDHEMCAGNI-EGG 760

  Fly   227 ADACQGDSGGPLAVRDE----LYGVVSWGNSCALPNYPGVYANVAYLRPWID 274
            .|:|||||||||....:    |.||.|||..||....||||..|:....||:
Zfish   761 NDSCQGDSGGPLVCYAQNTFVLQGVTSWGLGCANAMKPGVYTRVSKFVDWIE 812

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zetaTry	NP_523691.1	Tryp_SPc	38..273	CDD:214473	83/243 (34%)
zetaTry	NP_523691.1	Tryp_SPc	39..276	CDD:238113	84/245 (34%)
plg	NP_958880.2	PAN_AP_HGF	31..104	CDD:238532
		KR	109..190	CDD:214527
		KR	190..270	CDD:214527
		KR	281..361	CDD:214527
		Kringle	376..453	CDD:306546
		KR	490..572	CDD:214527
		Tryp_SPc	589..813	CDD:238113	84/245 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910