DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zetaTry and Tmprss3

DIOPT Version :9

Sequence 1:	NP_523691.1	Gene:	zetaTry / 36216	FlyBaseID:	FBgn0011556	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	XP_038954650.1	Gene:	Tmprss3 / 309665	RGDID:	1310135	Length:	454	Species:	Rattus norvegicus

Alignment Length:	257	Identity:	87/257 - (33%)
Similarity:	126/257 - (49%)	Gaps:	49/257 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 RIVGGYATDIAQVPYQISLRYKGITTPENPFRHRCGGSIFNETTIVTAAHCV------------I 90
            |||||..:.:.|.|:|:||:::|.        |.||||:.....||||||||            :
  Rat   216 RIVGGNVSSLTQWPWQVSLQFQGY--------HLCGGSVITPLWIVTAAHCVYDLYHPKSWTVQV 272

  Fly    91 GTVASQYKVVAGTNFQTGSDGVITNVKEIVMHEGYYSGAAYNNDIAILFVDPPLPLNNFTIKAIK 155
            |.|:..            ...|.:::.|.:::...|......||||::.:..||..:. ||:.|.
  Rat   273 GLVSLM------------DSPVPSHLVEKIIYHSKYKPKRLGNDIALMKLSEPLTFDE-TIQPIC 324

  Fly   156 L--ALEQPIEGTVSKVSGWGTTSPG-GYSSNQLLAVDVPIVSNELCDQDYEDFGDETYR--ITSA 215
            |  :.|...:|.:...||||.|..| |.:|..|....||::||::|:.      .:.|.  |:.:
  Rat   325 LPNSEENFPDGKLCWTSGWGATEDGAGDASPVLNHAAVPLISNKICNH------RDVYGGIISPS 383

  Fly   216 MLCAGKRGVGGADACQGDSGGPLAVRD----ELYGVVSWGNSCALPNYPGVYANVAYLRPWI 273
            |||||.. .||.|:|||||||||..::    :|.|..|:|..||..|.||||..:.....||
  Rat   384 MLCAGYL-KGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRITSFLDWI 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zetaTry	NP_523691.1	Tryp_SPc	38..273	CDD:214473	85/255 (33%)
zetaTry	NP_523691.1	Tryp_SPc	39..276	CDD:238113	86/256 (34%)
Tmprss3	XP_038954650.1	LDLa	74..107	CDD:238060
		SRCR_2	112..211	CDD:406055
		Tryp_SPc	216..444	CDD:214473	85/255 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910