Protein Alignment zetaTry and HGFAC

DIOPT Version :10

• Sequence 1: NP_523691.1
• Gene: zetaTry / 36216
• FlyBaseID: FBgn0011556
• Length: 280
• Species: Drosophila melanogaster
• Sequence 2: NP_001284368.1
• Gene: HGFAC / 3083
• HGNCID: 4894
• Length: 662
• Species: Homo sapiens
• Alignment Length: 271
• Identity: 81/271 - (29%)
• Similarity: 120/271 - (44%)
• Gaps: 69/271 - (25%)

  Fly    38 RIVGGYATDIAQVPYQISLRYKGITTPENPFRHRCGGSIFNETTIVTAAHCVI-GTVASQYKVVA 101
            ||:||.::.....|:..:: |.|     :.|   |.||:.:...:|:||||.. ........||.
Human   414 RIIGGSSSLPGSHPWLAAI-YIG-----DSF---CAGSLVHTCWVVSAAHCFSHSPPRDSVSVVL 469

  Fly   102 GTNFQTGSDGVITNVKEIVMHEGYYSGAAY------NNDIAIL--------------FVDP---P 143
            |.:|...:    |:|.:....|.|.....|      ::|:.::              ||.|   |
Human   470 GQHFFNRT----TDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICLP 530

  Fly   144 LPLNNFTIKAIKLALEQPIEGTVSKVSGWG--TTSPGGYSSNQLLAVDVPIVSNELCDQDYEDFG 206
            .|.:.|.            .|...:::|||  ..:..||||:...|: ||:|::..|... |.:|
Human   531 EPGSTFP------------AGHKCQIAGWGHLDENVSGYSSSLREAL-VPLVADHKCSSP-EVYG 581

  Fly   207 DETYRITSAMLCAG----KRGVGGADACQGDSGGPLAVRDE----LYGVVSWGNSCALPNYPGVY 263
            .:   |:..|||||    |     :||||||||||||....    |||::|||:.|...:.||||
Human   582 AD---ISPNMLCAGYFDCK-----SDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLHKPGVY 638

  Fly   264 ANVAYLRPWID 274
            ..||....||:
Human   639 TRVANYVDWIN 649

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
zetaTry	NP_523691.1	Tryp_SPc	38..273	CDD:214473	79/268 (29%)
HGFAC	NP_001284368.1	PRK14954	<32..>100	CDD:184918
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	64..102
		FN2	102..148	CDD:128373
		EGF_CA	162..197	CDD:238011
		FN1	200..240	CDD:238018
		EGF_CA	245..278	CDD:238011
		Kringle	286..367	CDD:395005
		Tryp_SPc	415..650	CDD:238113	80/270 (30%)