DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zetaTry and Tmprss11e

DIOPT Version :9

Sequence 1:	NP_523691.1	Gene:	zetaTry / 36216	FlyBaseID:	FBgn0011556	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	XP_038948843.1	Gene:	Tmprss11e / 305265	RGDID:	1561698	Length:	444	Species:	Rattus norvegicus

Alignment Length:	253	Identity:	92/253 - (36%)
Similarity:	128/253 - (50%)	Gaps:	43/253 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 RIVGGYATDIAQVPYQISLRYKGITTPENPFRHRCGGSIFNETTIVTAAHCV-IGTVASQYKVVA 101
            |||||.:.:..:.|:|.||::.|        .||||.::.:.|.:|:||||. .....|::....
  Rat   212 RIVGGTSAEEGEWPWQSSLQWDG--------SHRCGATLISNTWLVSAAHCFRTHKDPSRWTASF 268

  Fly   102 GTNFQTGSDGVITNVKEIVMHEGYYSGAAYNNDIAILFVDPPLPLNNFTIKAI-KLALE------ 159
            |...|...  :.|.::.|::|| .|:..:::.|||::.:..|:|..|    |: |:.|.
  Rat   269 GATLQPPK--LTTGIRRIIVHE-KYNYPSHDYDIALVELSRPVPCTN----AVHKVCLPDANHEF 326

  Fly   160 QPIEGTVSKVSGWGTTSPGGYSSNQLLAVDVPIVSNELCD--QDYEDFGDETYRITSAMLCAG-- 220
            ||  |....|:|:|.....|::.|.|..|.|..:..:.|:  |.|..      .||..|||||
  Rat   327 QP--GQRMFVTGFGALRNDGFAQNYLRQVQVDYIDTQTCNRPQSYNG------AITPRMLCAGFL 383

  Fly   221 KRGVGGADACQGDSGGPLA---VRDELY--GVVSWGNSCALPNYPGVYANVAYLRPWI 273
            |   |..|||||||||||.   |||..|  ||||||:.|..||.||||..|...|.||
  Rat   384 K---GEKDACQGDSGGPLVTPDVRDVWYLAGVVSWGDECGQPNKPGVYTRVTAFRDWI 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zetaTry	NP_523691.1	Tryp_SPc	38..273	CDD:214473	90/251 (36%)
zetaTry	NP_523691.1	Tryp_SPc	39..276	CDD:238113	91/252 (36%)
Tmprss11e	XP_038948843.1	SEA	71..176	CDD:396113
Tmprss11e	XP_038948843.1	Tryp_SPc	213..441	CDD:238113	91/252 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910