Protein Alignment zetaTry and GZMH

DIOPT Version :9

• Sequence 1: NP_523691.1
• Gene: zetaTry / 36216
• FlyBaseID: FBgn0011556
• Length: 280
• Species: Drosophila melanogaster
• Sequence 2: NP_219491.1
• Gene: GZMH / 2999
• HGNCID: 4710
• Length: 246
• Species: Homo sapiens
• Alignment Length: 290
• Identity: 75/290 - (25%)
• Similarity: 121/290 - (41%)
• Gaps: 68/290 - (23%)

  Fly     9 LLAFLVSLVALTQGLPLLEDLDEKSVPDGRIVGGYATDIAQVPYQISLRYKGITTPENPFRHRCG 73
            |||||::..|.|:                .|:||:.......||...:::.     :...|.|||
Human     7 LLAFLLTPGAGTE----------------EIIGGHEAKPHSRPYMAFVQFL-----QEKSRKRCG 50

  Fly    74 GSIFNETTIVTAAHCVIGTVASQYKVVAGTNFQTGSDGVITNVKEIVMHEGY-----------YS 127
            |.:..:..::|||||    ..|...|..|.:          |:||....:.:           |:
Human    51 GILVRKDFVLTAAHC----QGSSINVTLGAH----------NIKEQERTQQFIPVKRPIPHPAYN 101

  Fly   128 GAAYNNDIAILFVDPPLPLNNFTIKAIKL--ALEQPIEGTVSKVSGWGTTSPGGYSSNQLLAV-- 188
            ...::|||.:|.::....... .::.::|  :..|...|.:..|:||      ||.|...||.
Human   102 PKNFSNDIMLLQLERKAKWTT-AVRPLRLPSSKAQVKPGQLCSVAGW------GYVSMSTLATTL 159

  Fly   189 -DVPIVSNELCDQDYEDFGDETYRITSAMLCAG--KRGVGGADACQGDSGGPLAVRDELYGVVSW 250
             :|.:...:.|..:....|:.: |.|.  :|.|  |:...|   .:|||||||..:|...|::|:
Human   160 QEVLLTVQKDCQCERLFHGNYS-RATE--ICVGDPKKTQTG---FKGDSGGPLVCKDVAQGILSY 218

  Fly   251 GNSCALPNYPGVYANVAYLRPWIDAVLAGL 280
            ||....|  ||||..|::..|||...:..|
Human   219 GNKKGTP--PGVYIKVSHFLPWIKRTMKRL 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
zetaTry	NP_523691.1	Tryp_SPc	38..273	CDD:214473	65/252 (26%)
		Tryp_SPc	39..276	CDD:238113	67/254 (26%)
GZMH	NP_219491.1	Tryp_SPc	21..242	CDD:238113	67/254 (26%)
		Mediates the preference for acidic residues at the P3' and P4' sites	46..48		1/1 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910