DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zetaTry and Habp2

DIOPT Version :9

Sequence 1:	NP_523691.1	Gene:	zetaTry / 36216	FlyBaseID:	FBgn0011556	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	NP_001001505.2	Gene:	Habp2 / 292126	RGDID:	1302979	Length:	558	Species:	Rattus norvegicus

Alignment Length:	282	Identity:	93/282 - (32%)
Similarity:	134/282 - (47%)	Gaps:	37/282 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 PLLE----------DLDEKSVPDGRIVGGYATDIAQVPYQISLRYKGITTPENPFRHRCGGSIFN 78
            |::|          ::.|.:|.  ||.||:.:...:.|:|:||:.....|...|..|.||||:.:
  Rat   289 PVMELPGFDSCGKTEMTEHAVK--RIYGGFKSTAGKHPWQVSLQTSLPLTTSMPQGHFCGGSLIH 351

  Fly    79 ETTIVTAAHCVIGTVASQYKVVAGTN--FQTGSDGVITNVKEIVMHEGYYS-GAAYNNDIAILFV 140
            ...::|||||. .......|||.|..  .:|.|......|::|:.:..|.. ....:||||:|.:
  Rat   352 PCWVLTAAHCT-DMSTKHLKVVLGDQDLKKTESHEQTFRVEKILKYSQYNERDEIPHNDIALLKL 415

  Fly   141 DP---PLPLNNFTIKAIKLALEQPIEGTVSKVSGWGTTSPGGYSSNQLLAVDVPIVSNELCD--Q 200
            .|   ...|.:..:|.:.|..:....||...:||||.|.. |..|.|||...|.:::|.||:  |
  Rat   416 KPVGGHCALESKYVKTVCLPSDPFPSGTECHISGWGVTET-GEGSRQLLDAKVKLIANALCNSRQ 479

  Fly   201 DYEDFGDETYRITSAMLCAGKRGVGGADACQGDSGGPLAVRDE----LYGVVSWGNSCALPNYPG 261
            .|:      :.|..:|:|||.....|:|.|||||||||....:    :||:||||..|.  ..||
  Rat   480 LYD------HTIDDSMICAGNLQKPGSDTCQGDSGGPLTCEKDGTYYVYGIVSWGQECG--KKPG 536

  Fly   262 VYANVAYLRPWIDAVL---AGL 280
            ||..|.....||...:   |||
  Rat   537 VYTQVTKFLNWIKTTMHKEAGL 558

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zetaTry	NP_523691.1	Tryp_SPc	38..273	CDD:214473	84/246 (34%)
zetaTry	NP_523691.1	Tryp_SPc	39..276	CDD:238113	85/248 (34%)
Habp2	NP_001001505.2	EGF_CA	71..107	CDD:238011
		KR	191..275	CDD:238056
		Tryp_SPc	312..551	CDD:238113	85/248 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910