DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zetaTry and Tmprss15

DIOPT Version :9

Sequence 1:	NP_523691.1	Gene:	zetaTry / 36216	FlyBaseID:	FBgn0011556	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	XP_038944148.1	Gene:	Tmprss15 / 288291	RGDID:	1311046	Length:	1028	Species:	Rattus norvegicus

Alignment Length:	290	Identity:	99/290 - (34%)
Similarity:	142/290 - (48%)	Gaps:	33/290 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 GLLAFLVSLVALTQGLPLLE----DLDEKSVPD---GRIVGGYATDIAQVPYQISLRYKGITTPE 65
            |.|....||......|.||:    ...||.|..   .:||||..|.....|:.::|.|:    ..
  Rat   751 GSLILTPSLQCSQDSLILLQCNHKSCGEKMVTQKVGPKIVGGSDTQAGAWPWVVALYYR----DR 811

  Fly    66 NPFRHRCGGSIFNETTIVTAAHCVI--GTVASQYKVVAGTNFQTG--SDGVITNVKEIVMHEGYY 126
            :..|..||.|:.:...:|:|||||.  ....:::..|.|.:.|:.  |..|:..|.:.::...:|
  Rat   812 SGDRLLCGASLVSSDWLVSAAHCVYRRNLDPTRWTAVLGLHMQSNLTSPQVVRRVVDRIVINPHY 876

  Fly   127 SGAAYNNDIAILFVDPPLPLNNFT--IKAIKLALEQP--IEGTVSKVSGWGTTS-PGGYSSNQLL 186
            ......||||::.::..:   |:|  |:.|.|..|..  ..|.:..::|||... ..|.:.:.|.
  Rat   877 DKRRKVNDIAMMHLEFKV---NYTDYIQPICLPEENQTFTPGRMCSIAGWGYNKINAGSTVDVLK 938

  Fly   187 AVDVPIVSNELCDQDYEDFGDETYRITSAMLCAGKRGVGGADACQGDSGGPLAVRDE----LYGV 247
            ..|||:||||.|.|...:     |.||.:|||||.. .||.|:|||||||||..::.    |.||
  Rat   939 EADVPLVSNEKCQQQLPE-----YDITESMLCAGYE-EGGTDSCQGDSGGPLMCQENNRWFLVGV 997

  Fly   248 VSWGNSCALPNYPGVYANVAYLRPWIDAVL 277
            .|:|..|||||:|||||.|:....||.:.|
  Rat   998 TSFGVQCALPNHPGVYARVSQFIEWIHSFL 1027

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zetaTry	NP_523691.1	Tryp_SPc	38..273	CDD:214473	86/247 (35%)
zetaTry	NP_523691.1	Tryp_SPc	39..276	CDD:238113	88/249 (35%)
Tmprss15	XP_038944148.1	SEA	54..155	CDD:214554
		LDLa	188..221	CDD:238060
		CUB	229..335	CDD:412131
		MAM	351..507	CDD:395504
		CUB	528..635	CDD:395345
		LDLa	647..681	CDD:238060
		Tryp_SPc	789..1025	CDD:238113	88/248 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910