DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zetaTry and Tmprss7

DIOPT Version :9

Sequence 1:	NP_523691.1	Gene:	zetaTry / 36216	FlyBaseID:	FBgn0011556	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	NP_001099352.2	Gene:	Tmprss7 / 288118	RGDID:	1304655	Length:	829	Species:	Rattus norvegicus

Alignment Length:	284	Identity:	88/284 - (30%)
Similarity:	129/284 - (45%)	Gaps:	56/284 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 DLDEKSVPDG-----------RIVGGYATDIAQVPYQISLRYKGITTPENPFRHRCGGSIFNETT 81
            |..::|..:|           |:|||..:.....|:|:||.:.|..        .||.|:.:...
  Rat   570 DCPDRSDEEGCGCSRSSPFLHRVVGGSDSQEGTWPWQVSLHFVGSA--------HCGASVISREW 626

  Fly    82 IVTAAHCVIGTVASQ---YKVVAGTNFQTGSDGVITNVKEIVMHEGYYSGAAYNNDIAILFVDPP 143
            :::||||..|...|.   :....|...| |:...::.|:.||:|| ||:...::.|||:|.:...
  Rat   627 LLSAAHCFHGNRLSDPTPWTAHLGMYVQ-GNAKFVSPVRRIVVHE-YYNSQTFDYDIALLQLSIA 689

  Fly   144 LPLNNFTIKAIKLALEQPI----------EGTVSKVSGWGTTSPGGYSSNQLL-AVDVPIVSNEL 197
            .|   .|::    .|.|||          .|....|:|||.........:.:| ..:|.::...:
  Rat   690 WP---ETLR----QLIQPICIPPVGQRVRSGEKCWVTGWGRRHEADSKGSPILQQAEVELIDQTV 747

  Fly   198 CDQDYEDFGDETYRITSAMLCAGKRGVGGADACQGDSGGPLAVRDE------LYGVVSWGNSCAL 256
            |...|.       .|||.|||||... |.:|||:|||||||:.|.:      |.|:||||..|..
  Rat   748 CVSTYG-------IITSRMLCAGVMS-GKSDACKGDSGGPLSCRRKSDGKWILTGIVSWGYGCGR 804

  Fly   257 PNYPGVYANVAYLRPWIDAVLAGL 280
            ||:||||..|:...|||...:..|
  Rat   805 PNFPGVYTRVSNFVPWIHKYVPSL 828

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zetaTry	NP_523691.1	Tryp_SPc	38..273	CDD:214473	82/254 (32%)
zetaTry	NP_523691.1	Tryp_SPc	39..276	CDD:238113	83/256 (32%)
Tmprss7	NP_001099352.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	30..49
		SEA	94..190	CDD:279699
		CUB	<257..345	CDD:238001
		LDLa	470..504	CDD:238060
		LDLa	545..580	CDD:238060	2/9 (22%)
		Tryp_SPc	591..821	CDD:214473	82/254 (32%)
		Tryp_SPc	592..823	CDD:238113	83/255 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910