DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zetaTry and Tmprss5

DIOPT Version :9

Sequence 1:	NP_523691.1	Gene:	zetaTry / 36216	FlyBaseID:	FBgn0011556	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	NP_695223.2	Gene:	Tmprss5 / 266681	RGDID:	628625	Length:	445	Species:	Rattus norvegicus

Alignment Length:	251	Identity:	100/251 - (39%)
Similarity:	130/251 - (51%)	Gaps:	34/251 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 RIVGGYATDIAQVPYQISLRYKGITTPENPFRHRCGGSIFNETTIVTAAHCVIG---TVASQYKV 99
            |||||.|....:.|:|.|:....        ||.||.|:.....:||||||:..   :..|.::|
  Rat   207 RIVGGQAVASGRWPWQASVMLGS--------RHTCGASVLAPYWVVTAAHCMYSFRLSRLSSWRV 263

  Fly   100 VAGTNFQTG---SDGVITNVKEIVMHEGYYSGAAYNNDIAILFVDPPLPLNNF--TIKAIKL-AL 158
            .||....:.   ..|  |.|::|:.|. .||...::.|:|:|.:..|:   ||  |:.|:.| |.
  Rat   264 HAGLVSHSAVRQHQG--TMVEKIIPHP-LYSAQNHDYDVALLQLRTPI---NFSDTVSAVCLPAK 322

  Fly   159 EQPI-EGTVSKVSGWGTTSPG-GYSSNQLLAVDVPIVSNELCDQDYEDFGDETYRITSAMLCAGK 221
            ||.. :|:...|||||.|.|. .:||:.|....||::|.:||:......|..|:|    |||||.
  Rat   323 EQHFPQGSQCWVSGWGHTDPSHTHSSDTLQDTMVPLLSTDLCNSSCMYSGALTHR----MLCAGY 383

  Fly   222 RGVGGADACQGDSGGPLAVRD----ELYGVVSWGNSCALPNYPGVYANVAYLRPWI 273
            .. |.||||||||||||....    .|.||||||..||.||.|||||.||....||
  Rat   384 LD-GRADACQGDSGGPLVCPSGDTWHLVGVVSWGRGCAEPNRPGVYAKVAEFLDWI 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zetaTry	NP_523691.1	Tryp_SPc	38..273	CDD:214473	98/249 (39%)
zetaTry	NP_523691.1	Tryp_SPc	39..276	CDD:238113	99/250 (40%)
Tmprss5	NP_695223.2	SRCR_2	106..203	CDD:406055
Tmprss5	NP_695223.2	Tryp_SPc	208..441	CDD:238113	99/250 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910