DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zetaTry and Plau

DIOPT Version :9

Sequence 1:	NP_523691.1	Gene:	zetaTry / 36216	FlyBaseID:	FBgn0011556	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	NP_037217.3	Gene:	Plau / 25619	RGDID:	3343	Length:	432	Species:	Rattus norvegicus

Alignment Length:	269	Identity:	85/269 - (31%)
Similarity:	129/269 - (47%)	Gaps:	49/269 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 PDGRIVGGYATDIAQVPY--QISLRYKGITTPENPFRHRCGGSIFNETTIVTAAHCVIG-TVASQ 96
            |..:||||..|.:...|:  .|.|:.||.:.|.    .:||||:.:...:.:|.||.:. ....:
  Rat   175 PRFKIVGGEFTVVENQPWFAAIYLKNKGGSPPS----FKCGGSLISPCWVASATHCFVNQPKKEE 235

  Fly    97 YKVVAG----TNFQTGSDGVITNVKEIVMHEGYYSGA-AYNNDIAILFV--------DPPLPLNN 148
            |.|..|    .::..|.  :...|:::::||.:.... |::||||:|.:        .|     :
  Rat   236 YVVYLGQSKRNSYNPGE--MKFEVEQLILHEDFSDETLAFHNDIALLKIRTSTGQCAQP-----S 293

  Fly   149 FTIKAIKLAL---EQPIEGTVSKVSGWGTTSPGGYSSNQLLAVD-VPIVSNELCDQDYEDFGDET 209
            .||:.|.|..   :.|. |:..:::|:|..|...|...:.|.:. |.|:|:|.|.|.:. :|.|
  Rat   294 RTIQTICLPPRFGDAPF-GSDCEITGFGQESATDYFYPKDLKMSVVKIISHEQCKQPHY-YGSE- 355

  Fly   210 YRITSAMLCAG----KRGVGGADACQGDSGGPLAV----RDELYGVVSWGNSCALPNYPGVYANV 266
              |...||||.    |     .|:|.|||||||..    |..|.|:||||:.||..|.||||..|
  Rat   356 --INYKMLCAADPEWK-----TDSCSGDSGGPLICNIDGRPTLSGIVSWGSGCAEKNKPGVYTRV 413

  Fly   267 AYLRPWIDA 275
            :|...||.:
  Rat   414 SYFLNWIQS 422

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zetaTry	NP_523691.1	Tryp_SPc	38..273	CDD:214473	82/262 (31%)
zetaTry	NP_523691.1	Tryp_SPc	39..276	CDD:238113	84/265 (32%)
Plau	NP_037217.3	Binds urokinase plasminogen activator surface receptor	34..57
		KR	67..152	CDD:238056
		Connecting peptide	152..178		1/2 (50%)
		Tryp_SPc	178..420	CDD:214473	82/262 (31%)
		Tryp_SPc	179..423	CDD:238113	84/265 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910