DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment zetaTry and Klkb1

DIOPT Version :9

Sequence 1:	NP_523691.1	Gene:	zetaTry / 36216	FlyBaseID:	FBgn0011556	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	NP_036857.2	Gene:	Klkb1 / 25048	RGDID:	67382	Length:	638	Species:	Rattus norvegicus

Alignment Length:	275	Identity:	93/275 - (33%)
Similarity:	136/275 - (49%)	Gaps:	56/275 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 LLEDLDEKSVPDGRIVGGYATDIAQVPYQISLRYKGITTPENPFRHRCGGSIFNETTIVTAAHC- 88
            ::|..|..:..:.|||||..:.:.:.|:|:||:.|.::.     .|.|||||.....|:|||||
  Rat   377 VVESSDCTTKINARIVGGTNSSLGEWPWQVSLQVKLVSQ-----NHMCGGSIIGRQWILTAAHCF 436

  Fly    89 ----------VIGTVASQYKVVAGTNFQTGSDGVITNVKEIVMHEGY-YSGAAYNNDIAILFVDP 142
                      :.|.:.:..::...|.|        :::||:::|:.| .|..:|  |||::.:..
  Rat   437 DGIPYPDVWRIYGGILNLSEITNKTPF--------SSIKELIIHQKYKMSEGSY--DIALIKLQT 491

  Fly   143 PLPLNNFTIKAIKLALEQPI-------EGTVSK---VSGWGTTSPGGYSSNQLLAVDVPIVSNEL 197
            ||   |:|      ..::||       ..|:..   |:|||.|...|.:.|.|....:|:|.||.
  Rat   492 PL---NYT------EFQKPICLPSKADTNTIYTNCWVTGWGYTKERGETQNILQKATIPLVPNEE 547

  Fly   198 CDQDYEDFGDETYRITSAMLCAGKRGVGGADACQGDSGGPLAV----RDELYGVVSWGNSCALPN 258
            |.:.|.|     |.||..|:|||.: .||.|||:|||||||..    |.:|.|:.|||..||...
  Rat   548 CQKKYRD-----YVITKQMICAGYK-EGGIDACKGDSGGPLVCKHSGRWQLVGITSWGEGCARKE 606

  Fly   259 YPGVYANVAYLRPWI 273
            .||||..||....||
  Rat   607 QPGVYTKVAEYIDWI 621

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zetaTry	NP_523691.1	Tryp_SPc	38..273	CDD:214473	89/260 (34%)
zetaTry	NP_523691.1	Tryp_SPc	39..276	CDD:238113	90/261 (34%)
Klkb1	NP_036857.2	APPLE	21..104	CDD:128519
		APPLE	111..194	CDD:128519
		APPLE	201..284	CDD:128519
		APPLE	292..375	CDD:128519
		Tryp_SPc	390..621	CDD:214473	89/260 (34%)
		Tryp_SPc	391..621	CDD:238113	88/259 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910