DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zetaTry and Tmprss11d

DIOPT Version :9

Sequence 1:	NP_523691.1	Gene:	zetaTry / 36216	FlyBaseID:	FBgn0011556	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	NP_663536.1	Gene:	Tmprss11d / 231382	MGIID:	2385221	Length:	417	Species:	Mus musculus

Alignment Length:	284	Identity:	94/284 - (33%)
Similarity:	137/284 - (48%)	Gaps:	49/284 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 VALTQGLPLLEDLDEKSV--------PD------GRIVGGYATDIAQVPYQISLRYKGITTPENP 67
            :|.:..:..|.|.|.::|        ||      .||:||...:....|:|:||:...:
Mouse   150 IAPSNEITSLTDQDTENVLTQECGARPDLITLSEERIIGGMQAEPGDWPWQVSLQLNNV------ 208

  Fly    68 FRHRCGGSIFNETTIVTAAHCVIGTVASQYKVVAGTNFQTGSDGVIT-------NVKEIVMHEGY 125
              |.|||::.:...::|||||        :|......:.|.:.||.|       .|:.|:.|:|
Mouse   209 --HHCGGALISNMWVLTAAHC--------FKSYPNPQYWTATFGVSTMSPRLRVRVRAILAHDG- 262

  Fly   126 YSGAAYNNDIAILFVDPPLPLN-NFTIKAIKLALEQPIEGTVSKVSGWGTTSPGGYSSNQLLAVD 189
            ||....:||||::.:|..:..: |.....:..|.:..|.|:|:.|:|||:.:.||.:...|...:
Mouse   263 YSSVTRDNDIAVVQLDRSVAFSRNIHRVCLPAATQNIIPGSVAYVTGWGSLTYGGNAVTNLRQGE 327

  Fly   190 VPIVSNELCDQDYEDFGDETYRITSAMLCAGKRGVGGADACQGDSGGPLAVRDE-----LYGVVS 249
            |.|:|:|.|:......|.    :...|||||.|. |..|||||||||||...|.     :.|:||
Mouse   328 VRIISSEECNTPAGYSGS----VLPGMLCAGMRS-GAVDACQGDSGGPLVQEDSRRLWFVVGIVS 387

  Fly   250 WGNSCALPNYPGVYANVAYLRPWI 273
            ||..|.|||.||||..|...|.||
Mouse   388 WGYQCGLPNKPGVYTRVTAYRNWI 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zetaTry	NP_523691.1	Tryp_SPc	38..273	CDD:214473	85/247 (34%)
zetaTry	NP_523691.1	Tryp_SPc	39..276	CDD:238113	86/248 (35%)
Tmprss11d	NP_663536.1	SEA	48..140	CDD:279699
		Tryp_SPc	185..411	CDD:214473	85/247 (34%)
		Tryp_SPc	186..414	CDD:238113	86/248 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910