DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zetaTry and Proc

DIOPT Version :9

Sequence 1:	NP_523691.1	Gene:	zetaTry / 36216	FlyBaseID:	FBgn0011556	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	XP_006525784.1	Gene:	Proc / 19123	MGIID:	97771	Length:	484	Species:	Mus musculus

Alignment Length:	275	Identity:	83/275 - (30%)
Similarity:	128/275 - (46%)	Gaps:	52/275 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 DLDEKSVPDGRIVGGYATDIAQVPYQISLRYKGITTPENPFRHRCGGSIFNETTIVTAAHCVIGT 92
            ||:::..||.|||.|..|.....|:|..|.       ::..:..|||.:.:.:.::||||||.||
Mouse   225 DLEDELEPDPRIVNGTLTKQGDSPWQAILL-------DSKKKLACGGVLIHTSWVLTAAHCVEGT 282

  Fly    93 V-----ASQYKVVAGTNFQTGSDGVITNVKEIVMHEGYYSGAAYNNDIAILFVDPPLPLNNFTIK 152
            .     ..:|.:....:::...|     :|||::|.. |:.::.:||||:|.:..|..|:. ||.
Mouse   283 KKLTVRLGEYDLRRRDHWELDLD-----IKEILVHPN-YTRSSSDNDIALLRLAQPATLSK-TIV 340

  Fly   153 AI-----KLALEQPIEGTVSKVSGWGTTSPGGYSSNQ-----------LLAVDVPIVSNELCDQD 201
            .|     .||.|....|..:.|:||      ||.|::           |..:.:|:|:...|.:.
Mouse   341 PICLPNNGLAQELTQAGQETVVTGW------GYQSDRIKDGRRNRTFILTFIRIPLVARNECVEV 399

  Fly   202 YEDFGDETYRITSAMLCAGKRGVGGADACQGDSGGPLAVRDE----LYGVVSWGNSCALPNYPGV 262
            .::.      ::..|||||..| ...|||.||||||:.|...    |.|:||||..|...|..|:
Mouse   400 MKNV------VSENMLCAGIIG-DTRDACDGDSGGPMVVFFRGTWFLVGLVSWGEGCGHTNNYGI 457

  Fly   263 YANVAYLRPWIDAVL 277
            |..|.....||.:.:
Mouse   458 YTKVGSYLKWIHSYI 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zetaTry	NP_523691.1	Tryp_SPc	38..273	CDD:214473	77/259 (30%)
zetaTry	NP_523691.1	Tryp_SPc	39..276	CDD:238113	78/261 (30%)
Proc	XP_006525784.1	GLA	50..110	CDD:214503
		EGF_CA	111..155	CDD:238011
		FXa_inhibition	163..198	CDD:373209
		Tryp_SPc	236..470	CDD:238113	78/260 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910