DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zetaTry and CLIPA5

DIOPT Version :9

Sequence 1:	NP_523691.1	Gene:	zetaTry / 36216	FlyBaseID:	FBgn0011556	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	XP_320729.4	Gene:	CLIPA5 / 1280861	VectorBaseID:	AGAP011787	Length:	397	Species:	Anopheles gambiae

Alignment Length:	236	Identity:	74/236 - (31%)
Similarity:	108/236 - (45%)	Gaps:	45/236 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 HRCGGSIFNETTIVTAAHCVIGTVASQYKVVAGTNFQTGSDGVI-----TNVKEIVMHEGYYSGA 129
            ::||||:.....::||||||.....:|..:.|| .:.|.::..:     ..|.|:::||. :...
Mosquito   163 YQCGGSVIAPNVVLTAAHCVFNKPKTQLLLRAG-EWDTQTEHELYMHQNRRVAEVILHEA-FDNE 225

  Fly   130 AYNNDIAILFVDPPLPLNNFTIKAIKLALEQPIEGTVSK-----VSGWGTTSPGGYSSNQLL--A 187
            :..||:|:|.:..|..|.. .::.|.|    |..||...     .||||....|.....|::  .
Mosquito   226 SLANDVALLTLAEPFQLGE-NVQPICL----PPSGTSFDYQHCFASGWGKDQFGKEGKYQVILKK 285

  Fly   188 VDVPIVSNELCDQDYEDFGDETYR---------ITSAMLCAGKRGVGGADACQGDSGGPLAV--- 240
            |::|:|.:..|        .||.|         :..:.||||  ||.|.|.|:||.|.||..
Mosquito   286 VELPVVPHAKC--------QETMRSQRVGNWFVLDQSFLCAG--GVAGQDMCRGDGGSPLVCPIP 340

  Fly   241 --RDELY--GVVSWGNSCALPNYPGVYANVAYLRPWIDAVL 277
              ....|  |:|:||..|.....||||.:||:||.|||..|
Mosquito   341 GSPTHYYQAGIVAWGLGCGEDGIPGVYGDVAFLRDWIDQQL 381

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zetaTry	NP_523691.1	Tryp_SPc	38..273	CDD:214473	70/230 (30%)
zetaTry	NP_523691.1	Tryp_SPc	39..276	CDD:238113	73/233 (31%)
CLIPA5	XP_320729.4	Tryp_SPc	135..380	CDD:238113	73/233 (31%)
CLIPA5	XP_320729.4	Tryp_SPc	135..377	CDD:214473	70/230 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910