DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zetaTry and CLIPB5

DIOPT Version :9

Sequence 1:	NP_523691.1	Gene:	zetaTry / 36216	FlyBaseID:	FBgn0011556	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	XP_313032.4	Gene:	CLIPB5 / 1273975	VectorBaseID:	AGAP004148	Length:	379	Species:	Anopheles gambiae

Alignment Length:	300	Identity:	95/300 - (31%)
Similarity:	139/300 - (46%)	Gaps:	47/300 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 SLVA-LTQGLPLLEDLDEKSV-PDGRIVGGYATDIAQVPYQISLRYKGITTPENPFRHRCGGSIF 77
            |||| :..|:.||....:..: ...||.||..|.|.:.|:...|:|   ..|.|.|...|||.:.
Mosquito    90 SLVAPVRVGVGLLPSPGQCGIQTSDRIFGGVNTRIDEFPWIALLKY---AKPNNVFGFHCGGVLI 151

  Fly    78 NETTIVTAAHCVIG------------------TVASQYKVVAGTNFQTGSDGVITNVKEIVMHEG 124
            |:..::||:|||.|                  |..:|.....|.:.......:...::..:.|..
Mosquito   152 NDRYVLTASHCVNGKDIPSTWNLAEVRLGEWDTSTAQDCEGLGDDVDCSPPPIDVPIEGKIPHPE 216

  Fly   125 YY-SGAAYNNDIAILFVDPPLPLNNFTIKAIKLALEQPIE-----GTVSKVSGWGTTSPGGYSS- 182
            |. :.|...||||:|.:...:|.::| ||.|.|.::..::     |...:|:|||.|:...:|:
Mosquito   217 YVPTSAEQYNDIALLRLQQSVPYSDF-IKPICLPMQAELKARDYVGFRMQVAGWGRTATARFSNV 280

  Fly   183 NQLLAVDVPIVSNELCDQDYEDFGDETYRITSAMLCAGKRGVGGADACQGDSGGPL-AVRDE--- 243
            .|.:|||.  ||.:.|:|.|:   .|...:..:.||||  |..|.|:||||||||| .|...
Mosquito   281 KQKVAVDG--VSLDACNQVYQ---REQVLLRQSQLCAG--GEAGKDSCQGDSGGPLTGVHTAGGL 338

  Fly   244 ----LYGVVSWG-NSCALPNYPGVYANVAYLRPWIDAVLA 278
                |.|:||:| ..|....:||||..|.....||.|.:|
Mosquito   339 QYWYLIGLVSFGPTPCGQAGWPGVYTKVDQYVDWITATIA 378

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zetaTry	NP_523691.1	Tryp_SPc	38..273	CDD:214473	84/268 (31%)
zetaTry	NP_523691.1	Tryp_SPc	39..276	CDD:238113	85/270 (31%)
CLIPB5	XP_313032.4	CLIP	33..87	CDD:288855
		Tryp_SPc	115..373	CDD:214473	84/268 (31%)
		Tryp_SPc	116..373	CDD:238113	83/267 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910