DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zetaTry and CLIPB1

DIOPT Version :9

Sequence 1:	NP_523691.1	Gene:	zetaTry / 36216	FlyBaseID:	FBgn0011556	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	XP_307756.2	Gene:	CLIPB1 / 1269160	VectorBaseID:	AGAP003251	Length:	372	Species:	Anopheles gambiae

Alignment Length:	266	Identity:	85/266 - (31%)
Similarity:	125/266 - (46%)	Gaps:	42/266 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 RIVGGYATDIAQVPYQISLR-YKGITTPENPFRHRCGGSIFNETTIVTAAHCVIGTVAS--QYKV 99
            |||||..:.|...|:...:: |||    .|.:...|||.:.:...::|||||:.|..::  .|:|
Mosquito   114 RIVGGGVSPIDGYPWLTRIQYYKG----SNRYGFHCGGVLIHNQYVLTAAHCIEGVPSTWIVYQV 174

  Fly   100 VAG-----TNFQTGSDGVITNVKEI-----VMHEGYY--SGAAYNNDIAILFVDPPLPLNNFTIK 152
            ..|     |......|.....|:::     |:|..||  :||.| ||||:|.:...:...:| |:
Mosquito   175 RLGEFDTTTTIDCVEDDCADPVRDVLINAYVVHPDYYKQNGADY-NDIALLQLSETVEFTDF-IR 237

  Fly   153 AIKLALEQP-----IEGTVSKVSGWGTTSPGGYSSNQLLAVDVPIVSNELCDQDYEDFGDETYRI 212
            .|.|...:.     :.|..:.|:|||.|. ...||.:.|.:.||:|.||:|   .:.|......|
Mosquito   238 PICLPTSEESRTVNLTGKYATVAGWGQTE-NSTSSTKKLHLRVPVVDNEVC---ADAFSSIRLEI 298

  Fly   213 TSAMLCAGKRGVGGADACQGDSGGPLAVRDE---------LYGVVSWG-NSCALPNYPGVYANVA 267
            ....||||  |..|.|:|:|||||||....:         |.|:||:| ..|.....||||..::
Mosquito   299 IPTQLCAG--GEKGKDSCRGDSGGPLMRYGDGRSSTKSWYLIGLVSFGLEQCGTDGVPGVYTRMS 361

  Fly   268 YLRPWI 273
            ....|:
Mosquito   362 EYMDWV 367

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zetaTry	NP_523691.1	Tryp_SPc	38..273	CDD:214473	84/264 (32%)
zetaTry	NP_523691.1	Tryp_SPc	39..276	CDD:238113	84/265 (32%)
CLIPB1	XP_307756.2	CLIP	32..85	CDD:288855
		Tryp_SPc	114..367	CDD:214473	84/264 (32%)
		Tryp_SPc	115..367	CDD:238113	83/263 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910