DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zetaTry and AgaP_AGAP013252

DIOPT Version :9

Sequence 1:	NP_523691.1	Gene:	zetaTry / 36216	FlyBaseID:	FBgn0011556	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	XP_003436670.1	Gene:	AgaP_AGAP013252 / 11175997	VectorBaseID:	AGAP013252	Length:	597	Species:	Anopheles gambiae

Alignment Length:	296	Identity:	80/296 - (27%)
Similarity:	128/296 - (43%)	Gaps:	45/296 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 GLLAFLVSLVAL-----TQGL---PLLEDLDEKSVPDGRIV-GGYATDIAQVPYQISLRYKGITT 63
            |.||.:....|:     |..|   ||  :..|:.|....:| .|..|.....|:..::.::..|.
Mosquito     7 GFLALIAVFCAIGEVRKTNALDTVPL--ECGERKVKTIYLVQHGTETKEGHWPWHTAIYHREQTN 69

  Fly    64 PENPFRHRCGGSIFNETTIVTAAHCVI---GTV-ASQYKVVAGTNFQTGSDGVIT---NVKEIVM 121
                |.:.|||||.:..||:|||||:.   |.: ..|..|..|.| |.....|.:   :.:::::
Mosquito    70 ----FEYVCGGSILDRNTILTAAHCLYTSRGLIKLDQLSVQVGRN-QLSEASVRSQEHHPEQLIV 129

  Fly   122 HEGYYSGAAYNNDIAILFVDPPLPLNNFTIKAIKLALEQPIE---GTVSKVSGWGTTSPGGYSSN 183
            |.| :|..:..:|||::.:...:.:..:.......:||..::   |....|.|:|.|..... |:
Mosquito   130 HPG-FSPNSVTDDIALIKLATDITMTRYVQPVCLWSLEPNLDLIVGRNGTVVGFGLTEHDRV-SD 192

  Fly   184 QLLAVDVPIVSNELC-DQDYEDFGDETYRITSAMLCAGKRGVGGADACQGDSGGPLAVR--DELY 245
            .|....:.:|.:..| :.|.:.:|   ..:|:.|.|.|  |..|...|.|||||.:...  |..|
Mosquito   193 YLRQAAIAVVDSWTCIESDRQVYG---VTLTANMYCGG--GKTGVSVCNGDSGGGMFFEHGDTWY 252

  Fly   246 --GVVSW------GNSCALPNYPGVYANVAYLRPWI 273
              ||||:      ...|....|. |:.:||..|.||
Mosquito   253 VRGVVSFMPLRENVGLCDGTKYT-VFTDVAKYRDWI 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zetaTry	NP_523691.1	Tryp_SPc	38..273	CDD:214473	68/256 (27%)
zetaTry	NP_523691.1	Tryp_SPc	39..276	CDD:238113	70/257 (27%)
AgaP_AGAP013252	XP_003436670.1	Tryp_SPc	47..287	CDD:214473	67/252 (27%)
		Tryp_SPc	48..287	CDD:238113	67/251 (27%)
		Tryp_SPc	334..575	CDD:214473
		Tryp_SPc	335..575	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910