DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zetaTry and tmprss2.15

DIOPT Version :9

Sequence 1:	NP_523691.1	Gene:	zetaTry / 36216	FlyBaseID:	FBgn0011556	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	XP_031752206.1	Gene:	tmprss2.15 / 101732233	XenbaseID:	XB-GENE-22065943	Length:	504	Species:	Xenopus tropicalis

Alignment Length:	275	Identity:	100/275 - (36%)
Similarity:	133/275 - (48%)	Gaps:	40/275 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LVSLVALTQGLPLLEDLDEKSVPDGRIVGGYATDIAQVPYQIS-LRYKGITTPENPFRHRCGGSI 76
            :|||..::.||        .:..|.|||||....:...|:|:. |:..|.:.      :.|||||
Frog   247 MVSLRCISCGL--------STKVDSRIVGGTPASVGDWPWQVELLKLVGTSI------YLCGGSI 297

  Fly    77 FNETTIVTAAHCVIGTVA--SQYKVVAGT-NFQTGSDGVITNVKEIVMHEGYYSGAAYNN--DIA 136
            .....||||||||.|:.:  |.:||.||: ..|:......| |:..::|..|   ::|..  |:|
Frog   298 ITPHWIVTAAHCVYGSTSTPSAFKVFAGSLTIQSYYSAGYT-VERALVHPSY---SSYTQIYDVA 358

  Fly   137 ILFVDPPLPLNNFTIKAIKLALEQP----IEGTVSKVSGWGTTSPGGYSSNQLLAVDVPIVSNEL 197
            :|.:...|.   ||.....:.|...    .||....:||||||:.||..|..|:|..|||:|:..
Frog   359 LLKLTAALV---FTTNLRPVCLPNVGMPWAEGQPCWISGWGTTAEGGSISKNLMAASVPIISSTT 420

  Fly   198 CDQDYEDFGDETYRITSAMLCAGKRGVGGADACQGDSGGPLAVRDE----LYGVVSWGNSCALPN 258
            |:|.....|    .|:|.|:|||... ||.|.|||||||||..:..    |.|..|||..||...
Frog   421 CNQAAVYGG----AISSTMMCAGYLS-GGTDTCQGDSGGPLVTKTNSLWWLVGDTSWGYGCARAY 480

  Fly   259 YPGVYANVAYLRPWI 273
            .||||.||.....||
Frog   481 KPGVYGNVTVFIEWI 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zetaTry	NP_523691.1	Tryp_SPc	38..273	CDD:214473	92/248 (37%)
zetaTry	NP_523691.1	Tryp_SPc	39..276	CDD:238113	93/249 (37%)
tmprss2.15	XP_031752206.1	LDLa	93..121	CDD:238060
		SRCR_2	164..259	CDD:406055	5/19 (26%)
		Tryp_SPc	265..498	CDD:238113	93/249 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910