DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment zetaTry and mst1

DIOPT Version :9

Sequence 1:	NP_523691.1	Gene:	zetaTry / 36216	FlyBaseID:	FBgn0011556	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	XP_004915630.2	Gene:	mst1 / 100494056	XenbaseID:	XB-GENE-487985	Length:	736	Species:	Xenopus tropicalis

Alignment Length:	261	Identity:	71/261 - (27%)
Similarity:	117/261 - (44%)	Gaps:	37/261 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 DEKSVPDGRIVGGYATDIAQVPYQISLRYKGITTPENPFRHRCGGSIFNETTIVTAAHCVIGTVA 94
            :::|....|||||..   ...|:.:|||       .....|.||||:..|..:::...|.....|
Frog   497 NDRSSQRTRIVGGMP---GNSPWTVSLR-------NRQGEHFCGGSLVKENWVISTRQCFSSCDA 551

  Fly    95 --SQYKVVAGTNFQTGS----DGVITNVKEIVMHEGYYSGAAYNNDIAILFVDPPLPLNNFTIKA 153
              |.|:.|.||.|:..|    |.....:.:||.       ...::.:.:|.::.|:.||: .:..
Frog   552 DLSGYQAVMGTLFKNPSPDDPDRQSVPISKIVC-------GPSDSSLVMLKLERPVTLNS-RVAL 608

  Fly   154 IKLALEQPI--EGTVSKVSGWGTTSPGGYSSNQLLAVDV-PIVSNELCDQDYEDFGDETYRITSA 215
            |.|..|:.|  |.|..:::|||.|  ||...:.:|.:.: .|:||:.|:::|.   .:..::...
Frog   609 ICLPPERYIVPEATKCEIAGWGDT--GGTGHDNVLKIAIFHIISNDECNKNYR---SQRNKVLDN 668

  Fly   216 MLCAGKRGVGGADACQGDSGGPLAVRDE----LYGVVSWGNSCALPNYPGVYANVAYLRPWIDAV 276
            .:|.....| ...||:||.|||||....    |.||:.....|...|.|.::..|:....||:.|
Frog   669 EMCTKPVPV-DVGACEGDYGGPLACLTHDCWVLEGVIVPARGCGKKNQPAIFTRVSVYVDWINKV 732

  Fly   277 L 277
            :
Frog   733 M 733

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zetaTry	NP_523691.1	Tryp_SPc	38..273	CDD:214473	67/247 (27%)
zetaTry	NP_523691.1	Tryp_SPc	39..276	CDD:238113	68/249 (27%)
mst1	XP_004915630.2	PAN_AP_HGF	36..114	CDD:238532
		KR	118..198	CDD:214527
		KR	201..279	CDD:214527
		KR	308..390	CDD:214527
		KR	397..474	CDD:412161
		Tryp_SPc	506..732	CDD:238113	68/249 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910